Results 101 to 110 of about 197,200 (292)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Abortion restrictions as a form of cascading collective trauma

open access: yesCritical Public Health
Reproductive coercion, sexual violence, and intimate partner violence are rooted in patriarchal norms, and represent serious physical and mental health threats.
Selina Hardt   +2 more
doaj   +1 more source

Response regarding Existential Issues in Sexual Medicine. The relation between death anxiety and hypersexuality [PDF]

open access: yes, 2018
The recent article published by Dr Watter, “Existential Issues in Sexual Medicine: The Relation Between Death Anxiety and Hypersexuality,” deals with an interesting issue: the unique relation between death and ...
Burri, Andrea   +4 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Typy starzenia się aktywnych edukacyjnie osób starszych w kontekście egzystencjalnym

open access: yesColloquium
Being very much engaged in educational activities, active older learners are a unique group. That is why it is interesting to study how these people age.
Artur Fabiś , Marcin Muszyński
doaj   +1 more source

Questions and Answers about Oppositions [PDF]

open access: yes, 2011
A general characterization of logical opposition is given in the present paper, where oppositions are defined by specific answers in an algebraic question-answer game. It is shown that opposition is essentially a semantic relation of truth values between
Schang, Fabien
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Triple-loop learning as foundation for profound change, individual cultivation, and radical innovation: Construction processes beyond scientific and rational knowledge. [PDF]

open access: yes
Purpose: How does new knowledge or profound change come about and which processes of construction are involved? This article aims at developing an epistemological as well as methodological framework which is capable of explaining how profound and radical
Peschl, Markus F.
core   +1 more source

Logicism, Possibilism, and the Logic of Kantian Actualism [PDF]

open access: yes, 2017
In this extended critical discussion of 'Kant's Modal Metaphysics' by Nicholas Stang (OUP 2016), I focus on one central issue from the first chapter of the book: Stang’s account of Kant’s doctrine that existence is not a real predicate.
Stephenson, Andrew
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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