Results 51 to 60 of about 8,575 (295)

A PEDAGOGY FOR PLAY: THEORETICAL CONSIDERATIONS AND OPERATIONAL GUIDELINES FOR AN EDUCATIONAL PERSPECTIVE 0–6

open access: yesCadernos Cedes, 2023
In Italy the 0-6 educational institutions have always been characterized as a split system; the 0-6 integrated system was born on a legislative level only recently (Law No. 107/2015; Dlgs. No. 65/2017).
Donatella Savio
doaj   +1 more source

Existential Issues of Committee Constructions. Part II

open access: yesBulletin of the South Ural State University. Ser. Computer Technologies, Automatic Control & Radioelectronics, 2018
Мазуров Владимир Данилович, ведущий научный сотрудник, Институт математики и механики им. Н.Н. Красовского Уральского отделения Российской академии наук; профессор, кафедра эконометрики и статистики Высшей школы экономики и менеджмента, Уральский федеральный университет им. первого Президента России Б.Н. Ельцина; г. Екатеринбург; vldmazurov@gmail.com.
Mazurov, Vl.D., Polyakova, E.Yu.
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Geometrias barrocas no romance Lavoura arcaica, de Raduan Nassar

open access: yesConfluenze, 2021
This work aims to analyze the novel Lavoura arcaica, by Raduan Nassar, with basis on the triadic relationship house-body-text, taking the baroque as a reading operator.
Jonatas Guimarães
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Reprezentări filosofice ale unității existenței: prin credință noetică și credință perceptivă

open access: yesStudii de Istorie a Filosofiei Româneşti, 2022
In the following paper, I suggest an interpretation of Petrovici’s and Merleau-Ponty’s philosophy, both of them structured in accordance with the concept of unity of existence (the world), itself given in a close relation with the idea about an ...
Viorel Cernica
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

On the use of marked syntax in four short stories written by Hispanic American writers: a functional perspective [PDF]

open access: yes, 2004
We are going to analyse the main syntactical processes of thematization and postponement in English in four short stories written by four different Hispanic American writers who wrote around the seventies: Rudolfo Anaya's The Force of Luck, Denise Chávez'
Martínez Lirola, María
core  

A Corpus-based Study on Chinese EFL Learners' Acquisition of English Existential Construction

open access: yes, 2016
This corpus-based study examines English existential construction used by intermediate and advanced level Chinese EFL (English as a Foreign Language) learners.
Zhang, Xiaorong
core   +1 more source

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