Results 51 to 60 of about 178,372 (291)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Cadernos Cedes, 2023 In Italy the 0-6 educational institutions have always been characterized as a split system; the 0-6 integrated system was born on a legislative level only recently (Law No. 107/2015; Dlgs. No. 65/2017).
Donatella Savio
doaj +1 more source
The copula and existential verbs in Qiang [PDF]
, 2010 This paper discusses the copula and existential verb constructions in Qiang, a Tibeto-Burman language of northern Sichuan ...
Huang, Chenglong, LaPolla, Randy J.
core
Complexity of Timeline-Based Planning over Dense Temporal Domains: Exploring the Middle Ground [PDF]
, 2018 In this paper, we address complexity issues for timeline-based planning over dense temporal domains. The planning problem is modeled by means of a set of independent, but interacting, components, each one represented by a number of state variables, whose
Bozzelli, Laura +3 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Push-Pull Block Puzzles are Hard
, 2017 This paper proves that push-pull block puzzles in 3D are PSPACE-complete to solve, and push-pull block puzzles in 2D with thin walls are NP-hard to solve, settling an open question by Zubaran and Ritt.
D Dor +5 more
core +1 more source
Distributed Graph Automata and Verification of Distributed Algorithms [PDF]
, 2014 Combining ideas from distributed algorithms and alternating automata, we introduce a new class of finite graph automata that recognize precisely the languages of finite graphs definable in monadic second-order logic.
Reiter, Fabian
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Reprezentări filosofice ale unității existenței: prin credință noetică și credință perceptivă
Studii de Istorie a Filosofiei Româneşti, 2022 In the following paper, I suggest an interpretation of Petrovici’s and Merleau-Ponty’s philosophy, both of them structured in accordance with the concept of unity of existence (the world), itself given in a close relation with the idea about an ...
Viorel Cernica
doaj
Oppositions in a line segment [PDF]
, 2018 Traditional oppositions are at least two-dimensional in the sense that they are built based on a famous bidimensional object called square of oppositions and on one of its extensions such as Blanch\'e's hexagon.
Costa-Leite, Alexandre
core +2 more sources