Results 61 to 70 of about 178,372 (291)
, 2013 Existential constructions are normally defined as sentences in which some entity is associated with some location giving rise to the so-called locative paradigm which also involves the locative and the possessive construction (cf. Freeze 2001). In spite of the apparent simplicity of this approach, the assumption of an allegedly universal locative ...
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Agreement, Case and Definiteness in Balkan Existential Constructions
Balcania et SlaviaThis paper discusses agreement and definiteness effects in existential constructions in Balkan existentials constructions. I build on the restriction on definiteness properties of existential pivots known as definiteness effect: post-copular pivots in
Frasson, Alberto
doaj +1 more source
Constituent structure of a Tagalog text [PDF]
, 2010 This paper is an inductive look at the constituents found in a randomly selected Tagalog text, Bob Ong’s Alamat ng Gubat (Makati City, MM: Visual Print Enterprises, 2004). The analysis is based on the full text, but we will only be able to go through the
LaPolla, Randy J.
core
, 2008 This arXived paper has two independant parts, that are improved and corrected versions of different parts of a single paper once named "On equations in relatively hyperbolic groups".
A. Kharlampovich +19 more
core +3 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Presentative Constructions in English and Lithuanian
Kalbotyra, 2002 The article focuses on the type of existential sentence which is known in linguistic literature as a presentative construction. This type is distinguished on functional grounds: its communicative function is to introduce a new entity into a discourse. In
Violeta Kahėdaitė
doaj
Existencialismus v Řezáčově Svědkovi
Česká LiteraturaThis study deals with existential elements in The Witness, a novel by Václav Řezáč. Its aim is to find and analyse these elements, to reveal the connection between this work by Václav Řezáč and the existentialist thought system, and ...
Anna Šetková
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source