Results 51 to 60 of about 655,566 (261)

Unification of Algorithms for Quantification and Unfolding

open access: yes, 2022
Quantification is the supervised learning task of predicting the prevalences of classes in a data sample. Physics literature knows the same task under a different name: unfolding.
Bunse,Mirko
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Validades Existenciais e Enigmas Relacionados

open access: yesDoisPontos, 2009
Logic does not have purely existential theorems: the only existential sentences that are valid are those with valid universal analogues. Here, we show indeed this is so, when properly interpreted: every existential validity has a simple universal ...
Edward H. Haeusler   +2 more
doaj  

Making Sense of Conflicting (Defeasible) Rules in the Controlled Natural Language ACE: Design of a System with Support for Existential Quantification Using Skolemization [PDF]

open access: yesProceedings of the 13th International Conference on Computational Semantics - Short Papers, 2019
We present the design of a system for making sense of conflicting rules expressed in a fragment of the prominent controlled natural language ACE, yet extended with means of expressing defeasible rules in the form of normality assumptions. The approach we describe is ultimately based on answer-set-programming (ASP); simulating existential quantification
Martin Diller   +2 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Query answering over disjunctive datalog with existential quantifiers [PDF]

open access: yes
The paper discusses the impact of adding existential quantifi- cation in the head of positive disjunctive Datalog rules. After introducing syntax and semantics of the resulting language, we provide a notion of instantiation, which has been proven to ...
Alviano, Mario   +3 more
core   +3 more sources

Meditative thinking and heideggerian response to humanity’s forgetfulness of being

open access: yesHo Chi Minh City Open University Journal of Science - Social Sciences
Human beings today are facing existential challenges precisely because the human person has forgotten to be with oneself. Humanity has challenged entities and failed to let others be in a meaningful way.
Resty Ruel Ventura Borjal
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Whoever I Am: On the Quality of Life

open access: yesReligions
What is the relation between quantification and the mysterious question of identity? What order of quality is proper to the inexplicable fact that one is oneself?
Nicola Masciandaro
doaj   +1 more source

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