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Pathological Mechanisms in Diabetes of the Exocrine Pancreas: What’s Known and What’s to Know [PDF]
Frontiers in Physiology, 2020 The clinical significance of diabetes arising in the setting of pancreatic disease (also known as diabetes of the exocrine pancreas, DEP) has drawn more attention in recent years. However, significant improvements still need to be made in the recognition,
Mark O Goodarzi, Ling Li, Xiangyun Zhu
exaly +4 more sources
Low Grade Islet but Marked Exocrine Pancreas Inflammation in an Adult with Autoimmune Pre-Diabetes [PDF]
Case Reports in Endocrinology, 2019 There is unexplained deficit in size and function of the exocrine pancreas in type 1 diabetes (T1D). We obtained pancreas from an individual with pre-T1D obtained at surgery and addressed the question, what is the relative inflammation in the exocrine ...
Hiroshi Nomoto +5 more
doaj +2 more sources
The pathogenic “symphony” in type 1 diabetes: A disorder of the immune system, β cells, and exocrine pancreas [PDF]
Cell Metabolism, 2023 Mark A Atkinson, Raghavendra Mirmira
exaly +2 more sources
Exocrine pancreas development in zebrafish
Developmental Biology, 2005 Although many of the genes that regulate development of the endocrine pancreas have been identified, comparatively little is known about how the exocrine pancreas forms. Previous studies have shown that exocrine pancreas development may be modeled in zebrafish.
Michael Pack
exaly +3 more sources
A Double-Hit Model of Early-Life Stress and High-Fat Feeding Reveals Enhanced Exocrine Pancreatic Remodeling [PDF]
BiologyAdverse childhood experiences are associated with long-term metabolic disturbances, yet their effects on the exocrine pancreas remain poorly understood.
Laura García-Orozco +2 more
doaj +2 more sources
Frontiers in Endocrinology, 2021 Anatomical proximity and functional correlations between the exocrine and endocrine pancreas warrant reciprocal effects between the two parts. Inflammatory diseases of the exocrine pancreas, such as acute or chronic pancreatitis, or the presence of ...
Eleonóra Gál +6 more
doaj +1 more source
Diabetes of the exocrine pancreas [PDF]
Journal of Gastroenterology and Hepatology, 2018 AbstractDiabetes of the exocrine pancreas (DEP) is a form of diabetes that occurs due to pancreatic disease. It is far more common than has been previously considered, with a recent study showing 1.8% of adults with new‐onset diabetes should have been classified as DEP.
Katie Wynne +2 more
openaire +5 more sources
FGF21 Is an Exocrine Pancreas Secretagogue [PDF]
Cell Metabolism, 2017 Steven Kliewer +2 more
exaly +2 more sources
Ultrasound echo-intensity predicts severe pancreatic affection in cystic fibrosis patients. [PDF]
PLoS ONE, 2015 Pancreatic destruction affects the majority of patients with cystic fibrosis. We aimed to relate ultrasound findings to exocrine pancreatic function and cystic fibrosis genotype.Patients with cystic fibrosis and a matched group of healthy controls were ...
Trond Engjom +5 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 The type 2 Ca2+-dependent activator protein for secretion (CAPS2/CADPS2) regulates dense-core vesicle trafficking and exocytosis and is involved in the regulated release of catecholamines, peptidergic hormones, and neuromodulators.
Yotaroh Sato +20 more
doaj +1 more source