Results 61 to 70 of about 135,933 (245)

Mouse pancreas tissue slice culture facilitates long-term studies of exocrine and endocrine cell physiology in situ. [PDF]

PLoS ONE, 2013
Studies on pancreatic cell physiology rely on the investigation of exocrine and endocrine cells in vitro. Particularly, in the case of the exocrine tissue these studies have suffered from a reduced functional viability of acinar cells in culture.
Anja Marciniak, Claudia Selck, Betty Friedrich, Stephan Speier   +3 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The Hidden Architecture of Pancreatic Ducts: 3D Anatomical Reconstruction and Its Implication on Pancreatic Resection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Postoperative pancreatic fistula (POPF) is a common complication after pancreatic surgery and its mechanisms remain incompletely understood. While the diameter of the main pancreatic duct is well‐known to be a risk factor of POPF, the impact of branch duct's (BD) anatomy is not known.
Sébastien Frey, Luisa Nogueira, Sébastien Gaujoux, Karim Manai, Lilian Pimont, Karl Baqué, Michel Rayar, Nicolas Bronsard, Alain Sauvanet, Patrick Baqué   +9 more
wiley   +1 more source

Gene delivery to pancreatic exocrine cells in vivo and in vitro

BMC Biotechnology, 2012
Background Effective gene transfer to the pancreas or to pancreatic cells has remained elusive although it is essential for studies of genetic lineage tracing and modulation of gene expression. Different transduction methods and viral vectors were tested
Houbracken Isabelle, Baeyens Luc, Ravassard Philippe, Heimberg Harry, Bouwens Luc   +4 more
doaj   +1 more source

VPA and TSA delay the development of exocrine pancreas.

, 2016
The development of exocrine pancreas was analyzed at 72 hpf, 96 hpf and 120 hpf. GFP fluorescence in embryos of the ElastaseA-GFP transgenic line: controls (A-D), embryos treated with 0.2 μM TSA (D-F). White arrows indicate the exocrine pancreas.
Marie Tohme (2266480), Xiao Yong Chen (2266474), Ling Li (38566), Laure Bernard (265713), Vincent Laudet (28250), François Bonneton (2266477)   +5 more
core   +1 more source

The Important Role of p21-Activated Kinases in Pancreatic Exocrine Function

Biology
The p21-activated kinases (PAKs) are a conserved family of serine/threonine protein kinases, which are effectors for the Rho family GTPases, namely, Rac/Cdc42. PAKs are divided into two groups: group I (PAK1–3) and group II (PAK4–6).
Irene Ramos-Alvarez, Robert T. Jensen
doaj   +1 more source

Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child

JPGN Reports, EarlyView.
Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga, Cara L. Mack, Michelle Saad, Dylan Applin, Maisam Abu‐El‐Haija, David Vitale, Zachary Graff, Gila Ginzburg   +7 more
wiley   +1 more source

The Cystic Fibrosis of Exocrine Pancreas [PDF]

Cold Spring Harbor Perspectives in Medicine, 2013
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is highly expressed in the pancreatic duct epithelia and permits anions and water to enter the ductal lumen. This results in an increased volume of alkaline fluid allowing the highly concentrated proteins secreted by the acinar cells to remain in a soluble state.
Wilschanski, Michael, Novak, Ivana
openaire   +3 more sources

Extended pancreas donor program - the EXPAND study rationale and study protocol [PDF]

, 2013
BACKGROUND: Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or ...
Bechstein, Wolf Otto, Carsten Dietz, Falk Rauchfuss, Holub, Ines, Peter Schenker, Heise, Michael, Volker Müller, Rauchfuss, Falk, Proneth, Andrea, Florian Zeman, Björn Nashan, Markus Guba, Banas, Bernhard, Stefan Thorban, Schemmer, Peter, Edward K Geissler, Stephan Kersting, Ströhlein, Michael A., Andreas A Schnitzbauer, Nashan, Björn, Jonas, Sven, Thomas Becker, Ines Holub, Johanna R Foerster, Andreas Pascher, Manekeller, Steffen, Viebahn, Richard, Müller, Volker, Thomas Vogel, Peter Schemmer, Bernhard Banas, Farkas, Stefan A., Andrea Proneth, Arbogast, Helmut, Schenker, Peter, Richard Viebahn, Thorban, Stefan, Jürgen Klempnauer, Silvio Nadalin, Axel O Rahmel, Vogel, Thomas, Becker, Thomas, Guba, Markus, Zeman, Florian, Kersting, Stephan, Michael Heise, Rahmel, Axel, Klempnauer, Jürgen, Schlitt, Hans J., Schnitzbauer, Andreas, Stefan A Farkas, Nadalin, Silvio, Sven Jonas, Steffen Manekeller, Helmut Arbogast, Hans J Schlitt, Dietz, Carsten, Michael A Ströhlein, Geissler, Edward K., Wolf O Bechstein, Foerster, Johanna R., Pascher, Andreas, Andrea Proneth   +62 more
core   +1 more source

Endoscopic findings in patients with Shwachman–Diamond syndrome: A report from the North American Shwachman–Diamond syndrome registry

JPGN Reports, EarlyView.
Abstract Objectives Shwachman–Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its endoscopic phenotype is poorly defined. We sought to characterize endoscopic findings in patients with genetically confirmed SDS. Methods Retrospective registry study of 45 patients with biallelic Shwachman–Bodian–Diamond syndrome mutations and ...
Elizabeth Korn, Jane Koo, Diana Schwarz, Meghan Haney, Juan Putra, Jaeson Kim, Leah Cheng, Sarah Steltz, Lois Schwarz, Sara Loveless, Richard Cooper, Claire Dusa, Kasiani C. Myers, Akiko Shimamura, Andrew Wehrman, Amit S. Grover   +15 more
wiley   +1 more source