Results 41 to 50 of about 21,403 (203)

Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]

, 2009
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
A. Meining, A. Umgelter, Baron, Beger, Bradley, Bradley, Branum, C. Prinz, Connor, Connor, Dellinger, Fernandez-del Castillo, Hartwig, Isenmann, J. Gaa, L. Ludwig, M. Bajbouj, McKay, Nathens, Nordback, R.M. Schmid, Sand, Sarr, Seewald, Seifert, Seifert, Tsiotos, Tzovaras, V. Becker, W. Huber, Werner, Whitcomb   +31 more
core   +1 more source

Pancreatic exocrine insufficiency in patients with chronic heart failure and its possible association with appetite loss. [PDF]

PLoS ONE, 2017
Appetite loss is one complication of chronic heart failure (CHF), and its association with pancreatic exocrine insufficiency (PEI) is not well investigated in CHF.We attempted to detect the association between PEI and CHF-induced appetite.Patients with ...
Tingting Xia, Xichen Chai, Jiaqing Shen
doaj   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

Advanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen, Zhihang Xu, Yiping Zou, Zhenlai Jiang, Yecheng Li, Taochen He, Hanlin Yin, Jiali Li, Yanfei An, Jiande Han, Yuqi Xie, Wei Gan, Yaolin Xu, Wenquan Wang, Junyi He, Haibo Wang, Wenchuan Wu, Zhenyu Ye, Wenhui Lou, Jihui Hao, Liang Liu, Jun Yu, Ning Pu   +22 more
wiley   +1 more source

Chronic pancreatitis: review and update of etiology, risk factors, and management [version 1; referees: 2 approved]

F1000Research, 2018
Chronic pancreatitis is a syndrome involving inflammation, fibrosis, and loss of acinar and islet cells which can manifest in unrelenting abdominal pain, malnutrition, and exocrine and endocrine insufficiency.
Angela Pham, Christopher Forsmark
doaj   +1 more source

A clinical case of exocrine pancreatic insufficiency in a patient with type 1 diabetes mellitus

Сахарный диабет, 2023
The pancreas belongs to the glands of mixed secretion and simultaneously performs both endo- and exocrine functions. Exocrine pancreatic insufficiency (EPI) is the general name for the malabsorption process caused by inadequate production and decreased ...
M. R. Ragimov, T. V. Nikonova, E. V. Marchenko, N. M. Malysheva, O. S. Derevyanko   +4 more
doaj   +1 more source

Pancreas and pancreatitis: Exocrine pancreatic insufficiency

Pediatric Pulmonology
AbstractExocrine pancreatic insufficiency (EPI) is highly prevalent among individuals with cystic fibrosis (CF). Individuals diagnosed with EPI are often labeled as having “pancreas insufficient cystic fibrosis (PI‐CF)” while those with normal exocrine function are labeled as “pancreas sufficient CF (PS‐CF).” This diagnosis of EPI relies on clinical ...
Mitchell L. Ramsey, Gary J. Galante
openaire   +2 more sources

Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low‐Grade Malignant Tumors: A Comparative Analysis Based on 75‐g Oral Glucose Tolerance Test

Annals of Gastroenterological Surgery, EarlyView.
Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee, Keiko Kamei, Chihoko Nobori, Yuta Yoshida, Takaaki Murase, Atsushi Takebe, Yuki Okuda, Naru Babaya, Yoshihisa Hiromine, Ippei Matsumoto   +9 more
wiley   +1 more source

Diagnostics and treatment of exocrine pancreatic insufficiency: clinical guidelines of the Russian gastroenterological Association

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
The aim of publication. To present the modern concept of etiology and pathogenesis of exocrine pancreatic insufficiency to general practitioners as well as with the established approach to diagnostics and treatment of this syndrome. Summary.
V. T. Ivashkin, I. V. Mayev, A. V. Okhlobystin, S. A. Alekseyenko, Ye. V. Beloborodova, Yu. A. Kucheryavy, T. L. Lapina, A. S. Trukhmanov, I. B. Khlynov, M. V. Chikunova, A. A. Sheptulin, O. S. Shifrin   +11 more
doaj   +1 more source

The Difficult Differential Diagnosis for A Pediatric Patient with Shwachman-Diamond Syndrome; A Case Report and Literature Review

Trends in Pediatrics, 2022
Shwachman-Diamond syndrome (SDS) is a rare autosomal recessive disease characterized by bone marrow dysfunction, exocrine pancreatic insufficiency and skeletal abnormalities. Persistent or intermittent neutropenia caused by bone marrow hypoplasia is the
Dilvin Çelik Ateş, Arzu Akyay, Zehra Şule Haskoloğlu, Ünsal Özgen   +3 more
doaj   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source