Results 131 to 140 of about 416,673 (167)
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Biochemical Medicine and Metabolic Biology, 1986
The effect of exogenous phosphocreatine on ischemic myocardium was studied in experimental infarction in rabbits and in total ischemia of pig heart tissue (in vitro). It is shown that single dose administration of phosphocreatine is followed by its rapid clearance from blood plasma (with a half lifetime of 4-6 min), but constantly high plasma ...
V G, Sharov +8 more
semanticscholar +5 more sources
The effect of exogenous phosphocreatine on ischemic myocardium was studied in experimental infarction in rabbits and in total ischemia of pig heart tissue (in vitro). It is shown that single dose administration of phosphocreatine is followed by its rapid clearance from blood plasma (with a half lifetime of 4-6 min), but constantly high plasma ...
V G, Sharov +8 more
semanticscholar +5 more sources
American Heart Journal, 1990
The cellular electrophysiologic effects of exogenous phosphocreatine (PCr) were analyzed to ascertain its purported antiarrhythmic properties during myocardial ischemia and reperfusion. Transmembrane potentials were recorded from isolated guinea pig papillary muscles and Purkinje fibers studied in vitro.
L V, Rosenshtraukh +3 more
semanticscholar +5 more sources
The cellular electrophysiologic effects of exogenous phosphocreatine (PCr) were analyzed to ascertain its purported antiarrhythmic properties during myocardial ischemia and reperfusion. Transmembrane potentials were recorded from isolated guinea pig papillary muscles and Purkinje fibers studied in vitro.
L V, Rosenshtraukh +3 more
semanticscholar +5 more sources
Molecular Reproduction and Development
ABSTRACTThe low resistance of boar sperm to cryopreservation dictates that addition antioxidants and energetic substances to the diluent to improve sperm quality is necessary. This study evaluated the effect of spermidine and phosphocreatine in combination on the quality, antioxidant capacity, and antiapoptotic‐like changes capacity of cryopreserved ...
Jingchun Li +4 more
semanticscholar +5 more sources
ABSTRACTThe low resistance of boar sperm to cryopreservation dictates that addition antioxidants and energetic substances to the diluent to improve sperm quality is necessary. This study evaluated the effect of spermidine and phosphocreatine in combination on the quality, antioxidant capacity, and antiapoptotic‐like changes capacity of cryopreserved ...
Jingchun Li +4 more
semanticscholar +5 more sources
Basic Research in Cardiology, 1991
The purpose of this study was to find out whether Ca2+ is necessary for the protective effect of phosphocreatine (PCr) on ischemic myocardium. Isolated Langendorff-perfused rat hearts were used in the study. When ischemic arrest was induced in Ca(2+)-free buffer, PCr did not exert a protective effect on ischemic myocardium.
E A, Konorev +4 more
openaire +3 more sources
The purpose of this study was to find out whether Ca2+ is necessary for the protective effect of phosphocreatine (PCr) on ischemic myocardium. Isolated Langendorff-perfused rat hearts were used in the study. When ischemic arrest was induced in Ca(2+)-free buffer, PCr did not exert a protective effect on ischemic myocardium.
E A, Konorev +4 more
openaire +3 more sources
The Journal of thoracic and cardiovascular surgery, 1987
In valve replacement operations on 78 patients with acquired heart disease, the efficiency of phosphocreatine in intraoperative protection of ischemic myocardium was evaluated by clinical, morphologic, and biochemical methods. Phosphocreatine (8 to 10 mmol/L) in a blood cardioplegic solution was used in operations on 41 patients; in the control group ...
M L, Semenovsky +6 more
openaire +3 more sources
In valve replacement operations on 78 patients with acquired heart disease, the efficiency of phosphocreatine in intraoperative protection of ischemic myocardium was evaluated by clinical, morphologic, and biochemical methods. Phosphocreatine (8 to 10 mmol/L) in a blood cardioplegic solution was used in operations on 41 patients; in the control group ...
M L, Semenovsky +6 more
openaire +3 more sources
The Journal of thoracic and cardiovascular surgery, 1987
A phosphorus 31-nuclear magnetic resonance method was used to study the effect of exogenous phosphocreatine on the isolated perfused rat heart. The hearts were chemically arrested by St. Thomas' Hospital solution and made totally ischemic for 35 minutes at 37 degrees C.
V G, Sharov +6 more
openaire +3 more sources
A phosphorus 31-nuclear magnetic resonance method was used to study the effect of exogenous phosphocreatine on the isolated perfused rat heart. The hearts were chemically arrested by St. Thomas' Hospital solution and made totally ischemic for 35 minutes at 37 degrees C.
V G, Sharov +6 more
openaire +3 more sources
Oxidative myocardial damage: Protective action of exogenous phosphocreatine
Bulletin of Experimental Biology and Medicine, 1990E. A. Konorev +3 more
openaire +2 more sources
Kardiologiya i serdechno-sosudistaya khirurgiya, 2020
S.N. Tereshchenko +2 more
openaire +2 more sources
S.N. Tereshchenko +2 more
openaire +2 more sources
[Pharmacokinetics and metabolic disposition of exogenous phosphocreatine in rats].
Yao xue xue bao = Acta pharmaceutica Sinica, 2012This article is report the study of the pharmacokinetics and metabolic disposition of exogenous phosphocreatine (PCr) in rats by means of an ion-pair HPLC-UV assay. PCr and its metabolite creatine (Cr) and related-ATP in rat plasma and red blood cell (RBC) were simultaneously determined.
Ling-Li, Zou +5 more
openaire +2 more sources