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CARDIOPROTECTIVE EFFECTS OF PHOSPHOCREATINE [PDF]

open access: yesВестник анестезиологии и реаниматологии, 2018
Goal of the review: to review theoretical and practical aspects of using exogenous phosphocreatine in the patients with cardio-vascular disorders in various clinical situations, given that phospho-transporting system disorders are the one of pathogenic ...
V. V. Lomivorotov   +3 more
doaj   +3 more sources

A clinical case of cardioprotective therapy with exogenous phosphocreatine during chemotherapy and anti HER2-neu therapy in a patient with breast cancer

open access: yesКлинический разбор в общей медицине, 2023
The authors describe a clinical observation of cardiotoxicity of anticancer targeted therapy in a young patient with HER2neu-positive breast cancer. The results of instrumental examinations demonstrating manifestations of cardiotoxicity are presented ...
Andrey L. Pylev   +2 more
doaj   +2 more sources

Skin phosphocreatine [PDF]

open access: yesSkin Research and Technology, 2007
Background/purpose: The skin has the unique ability to survive ischemia associated with skin grafts, flaps and hair transplantation procedures. Spectroscopic data later confirmed by chromatography, immunohistochemistry and molecular biology techniques identified the presence of large quantities of phosphocreatine in human skin.
exaly   +3 more sources

The Protective Effect of Cx43 Protein-Mediated Phosphocreatine on Myocardial Ischemia/Reperfusion Injury

open access: yesCardiology Research and Practice, 2021
Objectives. To verify the protective effect of phosphocreatine on myocardium in an ischemic model and the possible mechanism of action. Methods. The model of myocardial ischemia/reperfusion (I/R) was established by the ligation balloon method. 30 SD rats
Chen-xi Wang   +11 more
doaj   +2 more sources

Population Pharmacokinetics of Phosphocreatine and Its Metabolite Creatine in Children With Myocarditis

open access: yesFrontiers in Pharmacology, 2020
Objective: This study aimed to develop a parent-metabolite joint population pharmacokinetic model to characterize the pharmacokinetic (PK) profile for phosphocreatine (PCr) and its metabolite creatine (Cr) in children with myocarditis and to use this ...
Libo Zhao, Meng Zhang, Yue Yuan
exaly   +3 more sources

In vivo imaging of phosphocreatine with artificial neural networks

open access: yesNature Communications, 2020
Phosphocreatine plays a vital role in cellular energetic homeostasis, but there are no routine diagnostic tests to noninvasively map the distribution with clinically relevant spatial resolution.
Lin Chen   +9 more
doaj   +2 more sources

Fusogenic Liposomes for the Intracellular Delivery of Phosphocreatine

open access: yesPharmaceuticals
Background/Objective: Maintaining intracellular adenosine triphosphate (ATP) levels is essential for numerous cellular functions, including energy metabolism, muscle contraction, and nerve impulse transmission.
Okhil K. Nag   +2 more
doaj   +3 more sources

The effectiveness of phosphocreatine cardioprotection during vascular surgery in high cardiac risk patients [PDF]

open access: yesВестник анестезиологии и реаниматологии
The objective was to study the occurrence of perioperative cardiovascular complications (CVС) and clinical and laboratory cardioprotection signs in patients treated with phosphocreatine infusion in intraoperative period of vascular surgery.Materials and ...
I. A. Kozlov   +2 more
doaj   +2 more sources

The metabolites for muscle and osteoclast activity are indicators of femoral neck osteoporosis [PDF]

open access: yesScientific Reports
Femoral neck osteoporosis is a critical risk factor for a bedbound state, which significantly decreases overall life expectancy, if a patient falls and suffers a fracture.
Masahiro Kameda   +2 more
doaj   +2 more sources

The effects of phosphocreatine disodium salts plus blueberry extract supplementation on muscular strength, power, and endurance

open access: yesJournal of the International Society of Sports Nutrition, 2021
Background Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance.
John Paul V. Anders   +10 more
doaj   +1 more source

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