Results 1 to 10 of about 44,180 (297)

The metabolites for muscle and osteoclast activity are indicators of femoral neck osteoporosis [PDF]

Scientific Reports
Femoral neck osteoporosis is a critical risk factor for a bedbound state, which significantly decreases overall life expectancy, if a patient falls and suffers a fracture.
Masahiro Kameda, Mitsuhiro Yanagida, Hiroshi Kondoh   +2 more
doaj   +2 more sources

Artificial mitochondria ameliorates osteoarthritis through restoring cellular energy metabolism homeostasis [PDF]

Bioactive Materials
Mitochondrial dysfunction under pathological or aging conditions disrupts adenosine triphosphate (ATP) synthesis, exacerbating disease progression by skewing energy metabolism toward catabolism.
Wenqiang Yan, Yu Chen, Haoda Wu, Zeyuan Gao, Xiaoqing Hu, Yingfang Ao, Chun Mao, Mimi Wan   +7 more
doaj   +2 more sources

Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart [PDF]

, 2014
Background: Multiple studies suggest creatine mediates anti-oxidant activity in addition to its established role in cellular energy metabolism.
Aksentijević, Dunja, Faller, Kiterie M.E., Lygate, Craig A., McAndrew, Debra J., Neubauer, Stefan, Schneider, Jurgen E., Zazueta, Cecilia, Zervou, Sevasti   +7 more
core   +10 more sources

The effects of phosphocreatine disodium salts plus blueberry extract supplementation on muscular strength, power, and endurance

Journal of the International Society of Sports Nutrition, 2021
Background Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance.
John Paul V. Anders, Tyler J. Neltner, Robert W. Smith, Joshua L. Keller, Terry J. Housh, F. Joseph Daugherty, Michael S. Tempesta, Alekha K. Dash, Daniel J. Munt, Richard J. Schmidt, Glen O. Johnson   +10 more
doaj   +1 more source

Development of Triiodothyronine Polymeric Nanoparticles for Targeted Delivery in the Cardioprotection against Ischemic Insult

Biomedicines, 2021
Ischemic heart disease is the main cause of death globally. Cardioprotection is the process whereby mechanisms that reduce myocardial damage, and activate protective factors, contribute to the preservation of the heart. Targeting these processes could be
Ozlem Ozen Karakus, Noureldien H. E. Darwish, Thangirala Sudha, Taher A. Salaheldin, Kazutoshi Fujioka, Peter C. Taylor Dickinson, Brian Weil, Shaker A. Mousa   +7 more
doaj   +1 more source

Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies

Cells, 2021
There is an important unmet need to develop interventions that improve outcomes of hypoxic-ischaemic encephalopathy (HIE). Creatine has emerged as a promising neuroprotective agent.
Nhi Thao Tran, Sharmony B. Kelly, Rod J. Snow, David W. Walker, Stacey J. Ellery, Robert Galinsky   +5 more
doaj   +1 more source

Energy System Contributions during Olympic Combat Sports: A Narrative Review

Metabolites, 2023
This narrative review focuses on the studies that estimate the energy systems’ contributions during match simulations of striking (boxing, karate, and taekwondo), grappling (judo), and weapon-based (fencing) Olympic combat sports.
Emerson Franchini
doaj   +1 more source

Creatine Kinase Activity as an Indicator of Energetic Impairment and Tissue Damage in Fish: A Review

Fishes, 2023
Creatine kinase (CK) is an enzyme that produces and uses phosphocreatine to transfer energy to maintain tissue and cellular energy homeostasis, being considered the main controller of cellular energy homeostasis.
Matheus D. Baldissera, Bernardo Baldisserotto   +1 more
doaj   +1 more source

Cardiovascular diseases and energy deficiency: pathogenetic ways of correction

Медицина неотложных состояний, 2023
Cardiovascular disease remains one of the most common and influential causes of death worldwide, as the heart plays a key role in the human body. Energetic cardioprotective therapy of the myocardium is an important protective factor, regulating the ...
M.S. Cherska, H.M. Kukharchuk
doaj   +1 more source

Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]

, 2020
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian, Clarke, Clare L., Gandy, Stephen, George, Jacob, Gingles, Christopher, Hutcheon, Anita, Nicholas, Richard S., Priba, Lukasz, Struthers, Allan D., Sumukadas, Deepa, Witham, Miles D.   +10 more
core   +2 more sources