Results 31 to 40 of about 44,180 (297)

Effects of Delivering Guanidinoacetic Acid or Its Prodrug to the Neural Tissue: Possible Relevance for Creatine Transporter Deficiency

open access: yesBrain Sciences, 2022
The creatine precursor guanidinoacetate (GAA) was used as a dietary supplement in humans with no adverse events. Nevertheless, it has been suggested that GAA is epileptogenic or toxic to the nervous system.
Enrico Adriano   +4 more
doaj   +1 more source

³¹P Saturation Transfer and Phosphocreatine Imaging in the Monkey Brain [PDF]

open access: yes, 1991
³¹P magnetic resonance imaging with chemical-shift discrimination by selective excitation has been employed to determine the phosphocreatine (PCr) distribution in the brains of three juvenile macaque monkeys.
Allman, John   +4 more
core   +1 more source

Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts

open access: yesPharmacology Research & Perspectives, 2019
Creatine transporter deficiency (CTD) is a metabolic disorder resulting in cognitive, motor, and behavioral deficits. Cyclocreatine (cCr), a creatine analog, has been explored as a therapeutic strategy for the treatment of CTD.
Kirill Gorshkov   +13 more
doaj   +1 more source

HUMAN IMMUNE SYSTEM AND PHYSICAL EXERCISE

open access: yesМедицинская иммунология, 2014
. Physiological and biochemical changes proceeding in muscles during physical loads exert systemic influence upon protein biosynthesis. This process is accelerated in presence of free amino acids, sufficient quantities of hormones, creatine, hydrogen ...
Z. Ch. Musin, S. V. Latukhov
doaj   +1 more source

Magnetic resonance spectroscopy in migraine: what have we learned so far? [PDF]

open access: yes, 2012
Objective: To summarize and evaluate proton (H-1) and phosphorus (P-31) magnetic resonance spectroscopy (MRS) findings in migraine. Methods: A thorough review of H-1 and/or P-31-MRS studies in any form of migraine published up to September 2011 ...
Achten, Eric   +2 more
core   +2 more sources

Cognitive-behavioral therapy for obsessive-compulsive disorder: access to treatment, prediction of long-term outcome with neuroimaging. [PDF]

open access: yes, 2015
This article reviews issues related to a major challenge to the field for obsessive-compulsive disorder (OCD): improving access to cognitive-behavioral therapy (CBT).
Feusner, Jamie D, O'Neill, Joseph
core   +2 more sources

Enzymatic Estimation of Phosphocreatine.

open access: yesExperimental Biology and Medicine, 1962
SummaryAn enzymatic micro-method has been described which permits simultaneous determination of adenosine triphosphate and phosphocreatine in extracts corresponding to 2-5 mg of muscle. The method has been found to be essentially in agreement with the colorimetric method of Fiske and Subbarow. Phosphocreatine in tissues containing more than 2% glycogen
E N, FAWAZ, G, FAWAZ, K, VON DAHL
openaire   +2 more sources

Recent Trends in Metabolomics by NMR Spectroscopy

open access: yesAngewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco   +6 more
wiley   +2 more sources

Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons [PDF]

open access: yes, 2020
BACKGROUND: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and development in ...
Bräuer, Anja U.   +7 more
core   +1 more source

Simultaneous Assessment of Skeletal Muscle Energetics and Blood Flow During Dynamic Exercise by Interleaved <sup>31</sup>P-MRS/<sup>1</sup>H-MRI. [PDF]

open access: yesMagn Reson Med
ABSTRACT Purpose To simultaneously measure skeletal muscle energetics and blood flow (BF) before, during, and after dynamic plantar flexion exercise (PFE). Methods Non‐localized pulse‐acquire phosphorus‐31 magnetic resonance spectroscopy (31P MRS) and phase contrast flow magnetic resonance imaging (1H MRI) using golden‐angle rotated spiral readouts ...
Samuel TJ   +6 more
europepmc   +2 more sources

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