Results 1 to 10 of about 416,673 (167)

Effect of exogenous phosphocreatine on cardiomycytic apoptosis and expression of Bcl-2 and Bax after cardiopulmonary resuscitation in rats. [PDF]

World J Emerg Med, 2011
Ischemia-reperfusion injury in the myocardium after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) is an important pathologic basis of post-cardiac arrest of syndrome (PCAS), and apoptosis is one of the major mechanisms in myocardial ischemia-reperfusion injury. To lessen myocardial ischemia-reperfusion injury after cardiac arrest and CPR,
Yan P, Chen SQ, Li ZP, Zhang J, Xue JK, Wang WT, Huang WJ, Cheng JY, Li HP.   +8 more
europepmc   +7 more sources

Protection of Exogenous Phosphocreatine for Myocardium in Percutaneous Coronary Intervention Related to Inflammation

Reviews in Cardiovascular Medicine, 2022
Objectives: Although injury of myocardium after percutaneous coronary intervention (PCI) has been reported, the mechanism and effect of exogenous phosphocreatine (PCr) supplementation on the injury are yet to be elucidated.
Ming-ying Ling, Yi-ping Song, Chun Liu, Zhi-hao Wang, Yan Wang, Xue-hui Li, Zhen Zhang, Rong-xiang Zhou, Liang-yi Qie, Man Li, Yun-ling Xiao, Huan-qin Chen, Yan-qiu Xing   +12 more
doaj   +4 more sources

Effectiveness of neoton in patients with chronic heart failure depending on the left ventricular ejection fraction. Sub-analysis of the BYHEART study

Российский кардиологический журнал, 2022
Aim. To study the effectiveness of exogenous phosphocreatine (EPCr) therapy in patients with heart failure (HF) with reduced and mildly reduce dejection fraction (EF).Material and methods.
S. N. Tereshchenko, I. A. Cheremisina, A. A. Safiullina   +2 more
doaj   +5 more sources

A clinical case of cardioprotective therapy with exogenous phosphocreatine during chemotherapy and anti HER2-neu therapy in a patient with breast cancer

Клинический разбор в общей медицине, 2023
The authors describe a clinical observation of cardiotoxicity of anticancer targeted therapy in a young patient with HER2neu-positive breast cancer. The results of instrumental examinations demonstrating manifestations of cardiotoxicity are presented ...
Andrey L. Pylev, Vyacheslav A. Lisovoy, Olga S. Kozlova   +2 more
doaj   +3 more sources

Role of Exogenous Phosphocreatine in Chemotherapy-induced Cardiomyopathy

Reviews in Cardiovascular Medicine, 2017
The 5-fluorouracil, doxorubicin, and cyclophosphamide (FAC) regimen is widely used in the management of breast cancer. The common cardiotoxic effects of doxorubicin include congestive heart failure and left ventricular dysfunction, and those of cyclophosphamide include pericarditis, myocarditis, and congestive heart failure. It has been postulated that
Swapnil, Parve, Gulnaz I, Aliakberova, Albert A, Gylmanov, Diana I, Abdulganieva   +3 more
semanticscholar   +5 more sources

Prophylaxis postoperative atrial fibrillation (POAF) with exogenous phosphocreatine in cardiac surgery [PDF]

Journal of Cardiothoracic and Vascular Anesthesia, 2020
Introduction Among all cardiovascular complications, new onset postoperative atrial fibrillation (POAF) is one of the most common complications, occurring in 30% to 50% of patients after cardiac surgery. (1) One of the possible mechanisms for the development of AF may be myocardial reperfusion after aortic unclamping (reperfusion arrhythmia).
V. Aliev, A. Yavorovskiy, A. Popov, E. Bulanova, R. Komarov   +4 more
openaire   +2 more sources

Use of exogenic phosphocreatine in ICU rehabilitation of patients with COVID-19 (pilot study)

Вестник анестезиологии и реаниматологии, 2022
The objective: to establish the possible effectiveness of exogenous phosphocreatine as a component of pharmacological support during the resuscitation stage of rehabilitation measures in critically ill patients with COVID-19.Subjects and Methods.
D. А. Krapivina, S. V. Voevodin, А. V. Chernyak, E. V. Grigoriev   +3 more
doaj   +3 more sources

Cardioprotection with the use of exogenous phosphocreatine in general surgery and critical conditions. Review

Annals of Critical Care, 2020
The number of surgeries performed for the elderly and senile persons with concomitant cardiovascular pathology is increasing every year. It is in this category of patients that the likelihood of developing perioperative cardiac complications is highest, which requires the use of cardioprotective measures to reduce the risk of their occurrence.
A. G. Yavorovskiy, Alexander M. Popov, P. V. Nogtev   +2 more
openaire   +2 more sources

Effect of exogenous phosphocreatine on the course of acute limb ischemia and reperfusion syndrome after arterial reconstruction in patients with vascular trauma

Медицина неотложных состояний
Background. Acute limb ischemia caused by traumatic arterial injury remains one of the most challenging problems of emergency vascular surgery. Restoration of blood flow may paradoxically provoke ischemia-reperfusion injury leading to limb loss.
O.B. Kutovyi, D.O. Kysilevskyi, S.I. Karpenko, O.V. Sokolov   +3 more
doaj   +2 more sources

Cardioprotective Efficacy of Exogenous Phosphocreatine after Global Ischemia in Open Heart Surgery in Patients with Reduced Left Ventricular Ejection Fraction: A Comparative Study

Кардиология в Беларуси, 2023
Введение. Проблема защиты миокарда (ЗМ) в условиях его глобальной ишемии во время полного пережатия аорты при операциях с искусственным кровообращением (ИК), несмотря на накопленный опыт, остается актуальной. Лечение экзогенным фосфокреатином (ФК) способствует защите миокарда от ишемической и реперфузионной альтерации.
Л.Г. Шестакова
openaire   +2 more sources