Results 161 to 170 of about 395,522 (295)

Genetic Correlates of Presenile Dementia and Cognitive Decline in the Armenian Population Following COVID-19: A Case-Control Study. [PDF]

Int J Mol Sci
Hovhannisyan Y, Yeritsyan H, Hakobjanyan G, Petrosyan G, Harutyunyan H, Muradyan A, Azizian A, Yenkoyan K.   +7 more
europepmc   +1 more source

Intermolecular exon ligation of the rRNA precursor of tetrahymena: Oligonucleotides can function as 5′ exons

, 1985
Tan Inoue, Francis X. Sullivan, Thomas R. Cech   +2 more
openalex   +1 more source

CircTP53/USP10/p53 signaling Axis as a Novel Regulator of Progression and Prognosis of Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang, Fen Chang, Zinan Li, Chengcheng Duan, Xiangkai Sun, Siyu Wang, Dongmin Wei, Wenming Li, Ye Qian, Shengda Cao, Juan Zhao, Dapeng Lei   +11 more
wiley   +1 more source

Exon [PDF]

, 2018
openaire   +2 more sources

Incorporating exon-exon junction reads enhances differential splicing detection. [PDF]

BMC Bioinformatics
Pham MT, Milevskiy MJG, Visvader JE, Chen Y.   +3 more
europepmc   +1 more source

Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter. [PDF]

, 1994
Hisahide Nishio, Yasuhiro Takeshima, Naoko Narita, Hiroshi Yanagawa, Yoshiyuki Suzuki, Yoshihiro Ishikawa, Yoshihiro Ishikawa, Rumi Minami, Hajime Nakamura, Masafumi Matsuo   +9 more
openalex   +1 more source

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

Advanced Science, EarlyView.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, Martina Morini, Martina Ardito, Alessandra Eva, Vincenza Cerbone, Lucia Mauriello, Marianna Caterino, Margherita Ruoppolo, John M. Maris, Sharon J. Diskin, Achille Iolascon, Mario Capasso   +20 more
wiley   +1 more source

Protocol to distinguish pre-mRNA from mRNA in RNA-protein interaction studies. [PDF]

STAR Protoc
Zeiler C, Bestehorn A, Kovarik P.
europepmc   +1 more source

Human monoamine oxidase A and B genes exhibit identical exon-intron organization. [PDF]

, 1991
Joseph Grimsby, Kevin Chen, L J Wang, N C Lan, Jason C.H. Shih   +4 more
openalex   +1 more source

POLE Deficiency Exacerbates Diesel Engine Exhaust‐Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells

Advanced Science, EarlyView.
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao   +8 more
wiley   +1 more source