Results 161 to 170 of about 838,049 (387)

Prevalence of asymptomatic malaria amongst pregnant women in sub-divisional hospital (CMA) Muea, Southwest Region, Cameroon

Exon
Background Gestational malaria has been defined as the presence of Plasmodium spp. in maternal peripheral blood or the finding of the parasite in the placenta.
Evaris Paddy Nchianang Fonyuy, Eleonore Ngounou, Jemea Lyonga Ngoisah, Rex Mbah Tendong, Constantine Ndikum Njikem, Elisabeth Menkem Zeuko'o   +5 more
doaj   +1 more source

Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. [PDF]

, 2019
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are associated with loss of nuclear transactive response DNA-binding protein 43 (TDP-43).
Artates, Jon W, Baughn, Michael W, Beccari, Melinda S, Bennett, C Frank, Cleveland, Don W, Da Cruz, Sandrine, Drenner, Kevin, Freyermuth, Fernande, Lagier-Tourenne, Clotilde, Lin, Nianwei, López-Erauskin, Jone, McMahon, Moira A, Melamed, Ze'ev, Ohkubo, Takuya, Ravits, John, Rigo, Frank, Rodriguez, Maria, Sun, Ying, Wu, Dongmei, Zhang, Ouyang   +19 more
core  

A novel SNP at exon 17 of INSR is associated with decreased insulin sensitivity in Chinese women with PCOS [PDF]

, 2006
Jin Li, Xiaoming Zhu, Qiong Luo, Yuli Qian, Fan Jin, Hefeng Huang   +5 more
openalex   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Transforming Pancreatic Cancer Diagnosis: Conventional Methods, Challenges, and Future Innovations

Exon
Pancreatic ductal adenocarcinoma (PDAC) is a well-known neoplasm that currently ranks seventh in cancer-related deaths worldwide and may occupy the second position by 2030.
Namita Sharma, Sudha Srivastava
doaj   +1 more source

mTOR-regulated U2af1 tandem exon splicing specifies transcriptome features for translational control [PDF]

, 2019
Jae-Woong Chang, Hsin-Sung Yeh, Meeyeon Park, Luke Erber, Jiao Sun, Sze Cheng, Alexander M Bui, Naima Ahmed Fahmi, Ryan A. Nasti, Rui Kuang, Yue Chen, Wei Zhang, Jeongsik Yong   +12 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Statistical Analysis of Cataract Disease: A Case Study of 15,221 Patients at the Niger Delta University Teaching Hospital, Okolobiri

Exon
Introduction: This research is on the statistical analysis of cataract disease between male and female patients. The objectives were to estimate the distribution of cataract disease over the years with respect to gender and measures the rate of patients ...
Ligeiaziba Sylva, Biu OE, Azowenunebi Quincy E   +2 more
doaj   +1 more source

Genetic Polymorphisms in Exon-3 region of Growth Hormone Gene in the Egyptian Goat Breeds [PDF]

, 2017
Nermin El‐Halawany, Fathy M. Abdelrazek, Yasmin A. El-Sayed, Afaf El-Werdany, Abd-El-Monsif Shawky, Ahmed Al-Tohamy, Hamdy Abdel-Shafy   +6 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source