Results 151 to 160 of about 838,175 (338)

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane   +4 more
wiley   +1 more source

Biodegradation of Petroleum Waste by Actinomycetes: Mechanisms, Applications, and Future Prospects

open access: yesExon
Actinomycetes are a specialized group of gram-positive, filamentous bacteria distinguished by their high G-C DNA content and an extraordinary capacity for bioremediation.
Dhruti Parejiya   +3 more
doaj   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

open access: yesAdvanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon   +6 more
wiley   +1 more source

Bioinformatics Approaches for Integrating Clinical and Environmental Data to Enhance Machine Learning Based Diabetes Risk Prediction

open access: yesExon
Diabetes is due to a variety of interacting factors including behavioral, metabolic and environmental ones. The large number of biomedical data collected in an increasingly multi-modal manner has given rise to many potential methods in bioinformatics to ...
Houda Harbaoui   +2 more
doaj   +1 more source

A database of orthologous exons in primates for comparative analysis of RNA-seq data [PDF]

open access: yes, 2012
RNA-seq technology facilitates the study of gene expression at the level of individual exons and transcripts. Moreover, RNA-seq enables unbiased comparative analysis of expression levels across species.
Ran Blekhman
core   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Assessment of Proximate, Mineral and amino acid Profile of Selected Agro-Allied By-Products Residues in Umuagwo, Imo State Nigeria

open access: yesExon
This study presents the first comparative analysis of proximate, mineral and amino acid composition of selected agricultural crop residues as potential feed ingredients in livestock and poultry production.
JohnPaul Nnawuike Azorji   +6 more
doaj   +1 more source

Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum. [PDF]

open access: yes, 2007
Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum (TCC) is a common and clinically distinct form of familial spastic paraplegia that is linked to the SPG11 locus on chromosome 15 in most affected families. We analyzed
AZZEDINE H   +24 more
core  

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Sustainable Conversion of Chitosan Waste into Nitrogen-Doped Graphene Quantum Dots: Green Synthesis Pathways and Biomedical Potential

open access: yesExon
The sustainable conversion of bio-waste into functional nanomaterials represents a critical step toward achieving circular material cycles and environmentally responsible innovation.
B Sooryakanth   +7 more
doaj   +1 more source

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