Results 171 to 180 of about 838,049 (387)

In Silico Screening of Phenylpropanoid and Polyketide Phytochemicals as Potential Inhibitors of Mpox Viral Proteins

Exon
Mpox, a viral zoonotic disease similar to smallpox, poses significant public health challenges, particularly in Africa, with recent outbreaks in regions like India emphasising its global threat.
Anishkiran Balasundar, Rajesh Parsanathan   +1 more
doaj   +1 more source

Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. [PDF]

, 2014
Lamins B1 and B2 (B-type lamins) have very similar sequences and are expressed ubiquitously. In addition, both Lmnb1- and Lmnb2-deficient mice die soon after birth with neuronal layering abnormalities in the cerebral cortex, a consequence of defective ...
Coffinier, Catherine, de Jong, Pieter J, Fong, Loren G, Jung, Hea-Jin, Lee, John M, Nobumori, Chika, Tatar, Angelica, Tu, Yiping, Wu, Daniel, Yoshinaga, Yuko, Young, Stephen G   +10 more
core  

Identification of an Intronic Splicing Enhancer Essential for the Inclusion of FGFR2 Exon IIIc [PDF]

, 2008
Puneet Seth, Heather B. Miller, Erika Lasda, James L. Pearson, Mariano A. García-Blanco   +4 more
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Edible coatings for enhancing the shelf-life of foods: meaningful or myth

Exon
In the current landscape, effective food management poses significant challenges, particularly in ensuring access to healthy, nutritious diets. Proper handling of food materials during post-harvest stages such as harvesting, packaging, transportation ...
Venkteshwar Yadav, Dharm Pal, Anil Kumar Poonia   +2 more
doaj   +1 more source

P668: PMP22 single exon deletion in a proband with hematologic malignancy and family history of Charcot-Marie-Tooth disease [PDF]

Katharina Schulze, Matthew Hoi Kin Chau, Hongzheng Dai, Elizabeth Mizerik, Keren Machol, Nichole Owen   +5 more
openalex   +1 more source

Complementary Sequence-Mediated Exon Circularization

Cell, 2014
Xiao-Ou Zhang, Hai-Bin Wang, Yang Zhang, Xuhua Lu, Ling-Ling Chen, Li Yang   +5 more
semanticscholar   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Anthrax the Most Lethal Bioterror: Synthesizing Knowledge and Insights for Researchers and Public Health Professionals

Exon
Anthrax, caused by Bacillus anthracis, poses a significant threat as both, a naturally occurring disease and a potent bioterrorism agent. This article comprehensively reviews anthrax, synthesizing historical context, biological characteristics, past ...
Saad Ahmed, Haris Ishtiaq Kiani
doaj   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source