Results 201 to 210 of about 395,522 (295)

Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review. [PDF]

Orphanet J Rare Dis
Shi X, Ye Z, Qian L, Hu W, Yang Y, He C, Huang Z, Wu B, Huang Y.   +8 more
europepmc   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Novel <i>FRMD6::PTH</i> chimera in tumorous bone lesion carrying a t(4;11;14;12)(q35;p15;q22;q13). [PDF]

Pathol Oncol Res
Panagopoulos I, Andersen K, Lloret I, Gorunova L, Lobmaier I.   +4 more
europepmc   +1 more source

Chick α tropomyosin gene contains three sets of mutually exclusive alternatively spliced exons

, 1989
Marguerite Lemonnier, Domenico Libri, Marc Fiszman   +2 more
openalex   +2 more sources

Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells? [PDF]

, 1991
Douglas L. Black
openalex   +1 more source

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Navigating beyond the surface - prognostic significance of KRAS, NRAS, BRAF, PIK3CA, and TP53 mutations examined by exons. [PDF]

Front Oncol
Afrăsânie VA, Marinca MV, Gafton B, Rusu A, Froicu EM, Sur D, Lungulescu CV, Popa RC, Afrăsânie I, Ivanov AV, Gîlcă-Blanariu GE, Miron L, Rusu C, Alexa-Stratulat T.   +13 more
europepmc   +1 more source

Identification of a Novel Neuronal C-SRC Exon Expressed in Human Brain [PDF]

, 1990
J M Pyper, Joseph B. Bolen
openalex   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Alternative splicing in the RBMXL1 5'-UTR induces uORF-mediated translation control in activated B lymphocytes. [PDF]

Sci Rep
de Breyne S, Polvèche H, Auboeuf D, Ohlmann T, Gruffat H, Manet E.   +5 more
europepmc   +1 more source