Results 201 to 210 of about 394,574 (252)

The exon junction complex coordinates the cotranscriptional inclusion of blocks of neighboring exons. [PDF]

Genes Dev
Bergfort A, Gordon JM, Gazzara MR, Hung CT, Lee B, Barash Y, Neugebauer KM.   +6 more
europepmc   +1 more source

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

Advanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang, Xuedong Wang, Mengyao Wang, Qian Zhou, Lusheng Wang, Shuai Cheng Li   +5 more
wiley   +1 more source

A novel heterozygous pathogenic variation in the <i>MECP2</i> gene causing typical Rett syndrome: a case report. [PDF]

Transl Pediatr
Zheng Y, Yang Y, He L, Chen H, Wang D, Chen Y.   +5 more
europepmc   +1 more source

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, Huansha Yu, Chen Wang, Xuan Wang, Haiyang Hu   +13 more
wiley   +1 more source

Molecular polymorphisms that underlie trait variation in crops: Lessons learned from soybean. [PDF]

Plant Genome
Espina MJC, Lorenz AJ, Stupar RM.
europepmc   +1 more source

Case Report: Complete response to the concurrent neoadjuvant radiation therapy and pembrolizumab in a locally recurrent, chemotherapy-refractory undifferentiated pleomorphic sarcoma of bone. [PDF]

Front Oncol
Patel BA, Smith JT, Wangsiricharoen S, Wang WL, Lin PP, Farooqi A, Nassif Haddad EF, Ummed K, Mericli AF, Adelman DM, Livingston JA, Conley AP.   +11 more
europepmc   +1 more source

A therapeutic antisense oligonucleotide encompassing 2'-<i>O</i>-methoxyethyl modification triggers unique perturbation of the transcriptome. [PDF]

NAR Mol Med
Ottesen EW, Murzyn WA, Kaas RL, Bertrand KJ, Payne JL, Singh RN.   +5 more
europepmc   +1 more source

Zipalertinib-A Novel Treatment Opportunity for Non-Small Cell Lung Cancers with Exon 20 Insertions and Uncommon EGFR Mutations. [PDF]

Cancers (Basel)
Dempke WCM, Fenchel K, Reinmuth N.
europepmc   +1 more source