Results 211 to 220 of about 404,647 (255)

Influence of Exon Duplication on Intron and Exon Phase Distribution

Journal of Molecular Evolution, 1998
Nonrandomness in the intron and exon phase distributions in a sample of 305 human genes has been found and analyzed. It was shown that exon duplications had a significant effect on the exon phase nonrandomness. All of the nonrandomness is probably due to both the processes of exon duplication and shuffling.
Larisa Fedorova
exaly   +3 more sources

Exons – Introns = Lexons: In‐frame concatenation of exons by PCR

Human Mutation, 1998
A method for concatenating exons from genomic DNA, thereby skipping large stretches of intron sequence, has been developed using the polymerase chain reaction (PCR) with primers based on known intron-exon junction sequences. The use of genomic DNA circumvents the need for cDNA preparation for many purposes, including cDNA construction and mutational ...
T M, Tuohy, J, Groden
openaire   +2 more sources

The universe of exons revisited

Genetica, 2003
We study the distribution of exons in eukaryotic genes to determine whether one can detect the reuse of exon sequences and to use the frequency of such reuse to estimate how many ancestral exon sequences there might have been. We use two databases of exons.
Serge, Saxonov, Walter, Gilbert
openaire   +2 more sources

Exons as enhancers

Nature Reviews Genetics, 2019
A study in Cell identifies a mechanism by which exon splicing can increase gene expression through the activation of weak upstream promoters.
openaire   +2 more sources