EXON RESINS: each one engineered for Specific Problems and Specific Uses [PDF]
, 1955 openalex +1 more source
Reassessing the Exon-Foldon correspondence using Frustration Analysis [PDF]
arXivProtein folding and evolution are intimately linked phenomena. Here, we revisit the concept of exons as potential protein folding modules across 38 abundant and conserved protein families. Taking advantage of genomic exon-intron organization and extensive protein sequence data, we explore exon boundary conservation and assess their foldon-like behavior
arxiv
Topological Entropy of DNA Sequences [PDF]
arXiv, 2011 Topological entropy has been one of the most difficult to implement of all the entropy-theoretic notions. This is primarily due to finite sample effects and high-dimensionality problems. In particular, topological entropy has been implemented in previous literature to conclude that entropy of exons is higher than of introns, thus implying that exons ...
arxiv
CTCF Degradation Causes Increased Usage of Upstream Exons in Mouse Embryonic Stem Cells [PDF]
arXiv, 2018 Transcriptional repressor CTCF is an important regulator of chromatin 3D structure, facilitating the formation of topologically associating domains (TADs). However, its direct effects on gene regulation is less well understood. Here, we utilize previously published ChIP-seq and RNA-seq data to investigate the effects of CTCF on alternative splicing of ...
arxiv
Information Analysis of DNA Sequences [PDF]
arXiv, 2010 The problem of differentiating the informational content of coding (exons) and non-coding (introns) regions of a DNA sequence is one of the central problems of genomics. The introns are estimated to be nearly 95% of the DNA and since they do not seem to participate in the process of transcription of amino-acids, they have been termed "junk DNA ...
arxiv
Finnish type of low density lipoprotein receptor gene mutation (FH-Helsinki) deletes exons encoding the carboxy-terminal part of the receptor and creates an internalization-defective phenotype. [PDF]
, 1989 Katriina Aalto‐Setälä +3 more
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Comparative analysis of the nucleotide composition biases in exons and introns of human genes [PDF]
arXiv, 2010 The nucleotide composition of human genes with a special emphasis on transcription-related strand asymmetries is analyzed. Such asymmetries may be associated with different mutational rates in two principal factors. The first one is transcription-coupled repair and the second one is the selective pressure related to optimization of the translation ...
arxiv
Gene structure for the alpha 1 chain of a human short-chain collagen (type XIII) with alternatively spliced transcripts and translation termination codon at the 5' end of the last exon. [PDF]
, 1988 Liisa Tikka +4 more
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