Results 291 to 300 of about 838,175 (338)

MYH11 variants in thoracic aortic aneurysm pathophysiology: From bench to bedside. [PDF]

Eur J Clin Invest
Atash A, Mees BME, Cramer MJ, Baas AF, Schurgers LJ, Doevendans PA, Stillitano F.   +6 more
europepmc   +1 more source

Fragment-Based Development of NSP14 Exonuclease Inhibitors Confounded by Batch-to-Batch Variability. [PDF]

ACS Chem Biol
Coker JA, Sun R, Polzer PM, Romigh T, Goins CM, Wang NS, Jung JU, Stauffer SR.   +7 more
europepmc   +1 more source

Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. [PDF]

Nat Commun
Kumari B, Damodaran AP, Guiblet WM, Xiao MS, Behera AK, On TA, McIntosh CE, Teszler M, Holloway C, Le S, Parab N, Zhao Y, Aregger M, Gonatopoulos-Pournatzis T.   +13 more
europepmc   +1 more source

Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth. [PDF]

Cell Death Discov
Davuluri VNG, Dias M, Llinas R, Neha K, Popli P, Hawkins SM, Tayade C, Courtois ET, Yalamanchili HK, Kommagani R.   +9 more
europepmc   +1 more source

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EGFR and HER2 exon 20 insertions in solid tumours: from biology to treatment

Nature Reviews Clinical Oncology, 2021
Alex Friedlaender, Vivek Subbiah, Alessandro Russo   +2 more
exaly   +2 more sources

Amivantamab plus Chemotherapy in NSCLC with EGFR Exon 20 Insertions.

New England Journal of Medicine, 2023
BACKGROUND Amivantamab has been approved for the treatment of patients with advanced non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertions who have had disease progression during or after platinum-based ...
Caicun Zhou, Ke-jing Tang, B. Cho, Baogang Liu, L. Paz-Ares, Susanna Y. Cheng, Satoru Kitazono, M. Thiagarajan, J. Goldman, J. Sabari, R. Sanborn, Aaron S. Mansfield, Jen-Yu Hung, Michael Boyer, Sanjay Popat, J. Mourão Dias, E. Felip, M. Majem, Mahmut Gumus, Sang-we Kim, A. Ono, John Xie, A. Bhattacharya, Trishala Agrawal, S. M. Shreeve, R. Knoblauch, Keunchil Park, Nicolas Girard   +27 more
semanticscholar   +1 more source

Alternative splicing and evolution: diversification, exon definition and function

Nature Reviews Genetics, 2010
Gil Ast
exaly   +2 more sources

The exon junction complex as a node of post-transcriptional networks

Nature Reviews Molecular Cell Biology, 2015
Hervé Le Hir, Jérôme Ôme Saulière
exaly   +2 more sources