Results 101 to 110 of about 30,223 (276)
ABSTRACT The Orchidaceae family, with its unparalleled species diversity among angiosperms, is integral to ornamental, medicinal, cultural, and ecological value. Multi‐omics techniques have proven invaluable for the identification of candidate genes and the advancement of functional genomics research. Nevertheless, the application of these technologies
Yonglu Wei +13 more
wiley +1 more source
ABSTRACT Mulberry is a representative economic tree species valued for both poverty alleviation and medicinal use. To advance the understanding of mulberry genomics and demography, we assembled high‐quality haploid genomes of two widely cultivated mulberry varieties NS14 and QS1, and analysed 376 accessions from 12 countries, including 39 ancient trees
Zhifeng Wang +19 more
wiley +1 more source
Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang +9 more
wiley +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Premature termination mutations in exon 3 of the SMN1 gene are associated with exon skipping and a relatively mild SMA phenotype [PDF]
Vittorio Sossi +7 more
openalex +1 more source
Assessing the effect of bovine MSTN variants on pre‐mRNA splicing
Abstract The myostatin protein is a potent negative regulator of skeletal muscle growth encoded by the MSTN gene. MSTN loss‐of‐function variants lead to a particular cattle phenotype characterized by an increase in skeletal muscle mass, known as “double muscling” or “double muscled”.
Nicolas Gaiani +2 more
wiley +1 more source
De Novo Variants in PPFIA2 in Individuals With Neurodevelopmental Disorders
ABSTRACT Liprin‐α2, encoded by PPFIA2, belongs to the family of Liprin‐α proteins which constitute major synaptic scaffolds participating in the assembly and maturation of synapses. Heterozygous de novo variants in PPFIA2 were identified by exome or genome sequencing in two unrelated individuals with a neurodevelopmental disorder.
Theresa Brunet +11 more
wiley +1 more source
Unexpected consequences: exon skipping caused by CRISPR-generated mutations [PDF]
Joshua J. Sharpe, Thomas A. Cooper
openalex +1 more source
Corticosteroid therapy in Duchenne muscular dystrophy: Management and new insights
Developmental Medicine &Child Neurology, EarlyView.
Claudia Brogna, Eugenio Mercuri
wiley +1 more source

