Results 11 to 20 of about 258,592 (266)
Royal Society Open Science, 2023 Target capture is widely used in phylogenomic, ecological and functional genomic studies. Bait sets that allow capture from a diversity of species can be advantageous, but high-sequence divergence from baits can limit yields.
Michael Forthman +2 more
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Evolutionary perspective of Big tau structure: 4a exon variants of MAPT
Frontiers in Molecular Neuroscience, 2022 The MAPT gene encoding the microtubule-associated protein tau can generate multiple isoforms by alternative splicing giving rise to proteins which are differentially expressed in specific areas of the nervous system and at different developmental stages.
Itzhak Fischer
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Frontiers in Marine Science, 2021 The octocoral genus Chrysogorgia (Duchassaing and Michelotti, 1864) contains 81 nominal species that are ecologically important components of benthic communities.
Candice Bobby Untiedt +8 more
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Plants, 2020 Palms are conspicuous floristic elements across the tropics. In continental Africa, even though there are less than 70 documented species, they are omnipresent across the tropical landscape.
Andrew J. Helmstetter +10 more
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The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer
Frontiers in Molecular Biosciences, 2018 Alternative splicing allows for the expression of multiple RNA and protein isoforms from one gene, making it a major contributor to transcriptome and proteome diversification in eukaryotes.
Ettaib El Marabti, Ihab Younis
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Identify alternative splicing events based on position-specific evolutionary conservation. [PDF]
PLoS ONE, 2008 The evolution of eukaryotes is accompanied by the increased complexity of alternative splicing which greatly expands genome information. One of the greatest challenges in the post-genome era is a complete revelation of human transcriptome with ...
Liang Chen, Sika Zheng
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The emergence of alternative 3' and 5' splice site exons from constitutive exons. [PDF]
PLoS Computational Biology, 2007 Alternative 3' and 5' splice site (ss) events constitute a significant part of all alternative splicing events. These events were also found to be related to several aberrant splicing diseases.
Eli Koren, Galit Lev-Maor, Gil Ast
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Characteristics of transposable element exonization within human and mouse [PDF]
PLoS ONE 5(6):e10907 2010, 2010 Insertion of transposed elements within mammalian genes is thought to be an important contributor to mammalian evolution and speciation. Insertion of transposed elements into introns can lead to their activation as alternatively spliced cassette exons, an event called exonization. Elucidation of the evolutionary constraints that have shaped fixation of
arxiv +1 more source
Splicing complexity as a pivotal feature of alternative exons in mammalian species
BMC Genomics, 2023 Background As a significant process of post-transcriptional gene expression regulation in eukaryotic cells, alternative splicing (AS) of exons greatly contributes to the complexity of the transcriptome and indirectly enriches the protein repertoires.
Feiyang Zhao +4 more
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Frontiers in Genetics, 2018 The Tibetan cashmere goat is one of the main goat breeds used by people living in the plateau. It exhibits the distinct phenotypic characteristics observed in lowland goats, allowing them to adapt to the challenging conditions at high altitudes.
Chandar Kumar +9 more
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