Results 11 to 20 of about 586,929 (366)

Detecting differential usage of exons from RNA-seq data [PDF]

Genome Research, 2012
RNA-seq is a powerful tool for the study of alternative splicing and other forms of alternative isoform expression. Understanding the regulation of these processes requires sensitive and specific detection of differential isoform abundance in comparisons
S. Anders, Alejandro Reyes, W. Huber
semanticscholar   +5 more sources

The "alternative" choice of constitutive exons throughout evolution. [PDF]

PLoS Genetics, 2007
Alternative cassette exons are known to originate from two processes-exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution.
Galit Lev-Maor, Amir Goren, Noa Sela, Eddo Kim, Hadas Keren, Adi Doron-Faigenboim, Shelly Leibman-Barak, Tal Pupko, Gil Ast   +8 more
doaj   +12 more sources

The contribution of Alu exons to the human proteome [PDF]

Genome Biology, 2016
BackgroundAlu elements are major contributors to lineage-specific new exons in primate and human genomes. Recent studies indicate that some Alu exons have high transcript inclusion levels or tissue-specific splicing profiles, and may play important ...
Lan Lin, Peng Jiang, J. Park, Jinkai Wang, Zhi-xiang Lu, M. Lam, P. Ping, Yi Xing   +7 more
semanticscholar   +3 more sources

All exons are not created equal—exon vulnerability determines the effect of exonic mutations on splicing

Nucleic Acids Research, 2023
Abstract It is now widely accepted that aberrant splicing of constitutive exons is often caused by mutations affecting cis-acting splicing regulatory elements (SREs), but there is a misconception that all exons have an equal dependency on SREs and thus a similar vulnerability to aberrant splicing.
Lise L. Holm, Thomas K. Doktor, Katharina K. Flugt, Ulrika S. S. Petersen, Rikke Pedersen, Brage S. Andresen   +5 more
openaire   +3 more sources

Low hybridization temperatures improve target capture success of invertebrate loci: a case study of leaf-footed bugs (Hemiptera: Coreoidea)

Royal Society Open Science, 2023
Target capture is widely used in phylogenomic, ecological and functional genomic studies. Bait sets that allow capture from a diversity of species can be advantageous, but high-sequence divergence from baits can limit yields.
Michael Forthman, Eric R. L. Gordon, Rebecca T. Kimball   +2 more
doaj   +1 more source

Unraveling the Phylogenomic Relationships of the Most Diverse African Palm Genus Raphia (Calamoideae, Arecaceae)

Plants, 2020
Palms are conspicuous floristic elements across the tropics. In continental Africa, even though there are less than 70 documented species, they are omnipresent across the tropical landscape.
Andrew J. Helmstetter, Suzanne Mogue Kamga, Kevin Bethune, Thea Lautenschläger, Alexander Zizka, Christine D. Bacon, Jan J. Wieringa, Fred Stauffer, Alexandre Antonelli, Bonaventure Sonké, Thomas L. P. Couvreur   +10 more
doaj   +1 more source

Identification and characterisation of single nucleotide polymorphisms in interferon regulatory factor-5 gene of Nigerian local chickens

Agricultura Tropica et Subtropica, 2021
The interferon regulatory factor gene family encodes transcription factors with multiple biological functions, which include reproduction, cell differentiation and immunity.
Durosaro Samuel Olutunde, Ozoje Michael Ohiokhuaobo, Adebambo Ayotunde Olutumininu, Onagbesan Okanlawon Mohamed   +3 more
doaj   +1 more source

Detection of internal exon deletion with exon Del [PDF]

BMC Bioinformatics, 2014
Exome sequencing allows researchers to study the human genome in unprecedented detail. Among the many types of variants detectable through exome sequencing, one of the most over looked types of mutation is internal deletion of exons. Internal exon deletions are the absence of consecutive exons in a gene.
Guo, Yan, Zhao, Shilin, Lehmann, Brian D, Sheng, Quanhu, Shaver, Timothy M, Stricker, Thomas P, Pietenpol, Jennifer A, Shyr, Yu   +7 more
openaire   +2 more sources

Phylogenetic Relationships Within Chrysogorgia (Alcyonacea: Octocorallia), a Morphologically Diverse Genus of Octocoral, Revealed Using a Target Enrichment Approach

Frontiers in Marine Science, 2021
The octocoral genus Chrysogorgia (Duchassaing and Michelotti, 1864) contains 81 nominal species that are ecologically important components of benthic communities.
Candice Bobby Untiedt, Candice Bobby Untiedt, Andrea M. Quattrini, Andrea M. Quattrini, Catherine S. McFadden, Phil A. Alderslade, Eric Pante, Eric Pante, Christopher P. Burridge   +8 more
doaj   +1 more source

Characteristics of transposable element exonization within human and mouse [PDF]

, 2010
Insertion of transposed elements within mammalian genes is thought to be an important contributor to mammalian evolution and speciation. Insertion of transposed elements into introns can lead to their activation as alternatively spliced cassette exons ...
A Athanasiadis, A Corvelo, A Gerber, A Goren, A Levy, A Magen, A Nekrutenko, A Resch, AFA Smit, Agnes Hotz-Wagenblatt, B Giardine, B Mersch, BR Graveley, Britta Mersch, C Liu, D Karolchik, D Labuda, DD Kim, E Kim, ES Lander, EY Levanon, G Ast, G Lev-Maor, G Lev-Maor, Gil Ast, H Xie, Ilya Ruvinsky, J Hull, J Jurka, J Jurka, JO Kriegs, JO Yang, JP Nemes, K Nakabayashi, KP Kister, L Lin, L Lin, M Amit, M Blow, M Krull, M Moller-Krull, M Roy, M Sironi, M Sironi, MA Batzer, MD Koob, N Gal-Mark, N Gal-Mark, N Sela, NH Gehring, Noa Sela, O Ram, P Deininger, PL Deininger, R Cordaux, R Sorek, R Sorek, R Sorek, RA Gibbs, RE Mills, RH Waterston, RM Kuhn, RT Hillman, S He, S Schwartz, SK Ng, SS Singer, ST Sherry, T Kwan, T Kwan, VV Kapitonov, W Makalowski, WJ Kent, WL Chen, WS Lo, XH Zhang, Y Xing, YF Chang   +77 more
core   +17 more sources