Results 11 to 20 of about 419,485 (330)
Exons, introns and DNA thermodynamics [PDF]
Physical Review Letters, 2005 The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis.
A. Stoltzfus +11 more
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POEM, A 3-dimensional exon taxonomy and patterns in untranslated exons [PDF]
BMC Genomics, 2008 Background The existence of exons and introns has been known for thirty years. Despite this knowledge, there is a lack of formal research into the categorization of exons.
Chonka Ashley, Knapp Keith, Chen Yi-Ping
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JuncDB: an exon–exon junction database [PDF]
Nucleic Acids Research, 2015 Intron positions upon the mRNA transcript are sometimes remarkably conserved even across distantly related eukaryotic species. This has made the comparison of intron-exon architectures across orthologous transcripts a very useful tool for studying various evolutionary processes.
Lotem Guy, Liran Carmel, Michal Chorev
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Molecular Cell, 2010 Pathways of intron/exon specification that drive spliceosome assembly remain unclear. In this issue of Molecular Cell, Schneider et al. (2010) extensively characterize complexes formed on exons, demonstrating unexpected components and providing insights into the switch from cross-exon to cross-intron interactions.
Charles C. Query, Alberto Moldón
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Nucleic Acids Research, 2023 Abstract It is now widely accepted that aberrant splicing of constitutive exons is often caused by mutations affecting cis-acting splicing regulatory elements (SREs), but there is a misconception that all exons have an equal dependency on SREs and thus a similar vulnerability to aberrant splicing.
Lise L. Holm +5 more
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Plants, 2020 Palms are conspicuous floristic elements across the tropics. In continental Africa, even though there are less than 70 documented species, they are omnipresent across the tropical landscape.
Andrew J. Helmstetter +10 more
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Evolutionary perspective of Big tau structure: 4a exon variants of MAPT
Frontiers in Molecular Neuroscience, 2022 The MAPT gene encoding the microtubule-associated protein tau can generate multiple isoforms by alternative splicing giving rise to proteins which are differentially expressed in specific areas of the nervous system and at different developmental stages.
Itzhak Fischer
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Frontiers in Marine Science, 2021 The octocoral genus Chrysogorgia (Duchassaing and Michelotti, 1864) contains 81 nominal species that are ecologically important components of benthic communities.
Candice Bobby Untiedt +8 more
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Detection of internal exon deletion with exon Del [PDF]
BMC Bioinformatics, 2014 Exome sequencing allows researchers to study the human genome in unprecedented detail. Among the many types of variants detectable through exome sequencing, one of the most over looked types of mutation is internal deletion of exons. Internal exon deletions are the absence of consecutive exons in a gene.
Brian D. Lehmann +7 more
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Comparative Analysis and Classification of Cassette Exons and Constitutive Exons [PDF]
BioMed Research International, 2017 Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon.
Ying Cui, Meng Cai, H. Eugene Stanley
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