Results 11 to 20 of about 255,773 (233)
Frontiers in Marine Science, 2021 The octocoral genus Chrysogorgia (Duchassaing and Michelotti, 1864) contains 81 nominal species that are ecologically important components of benthic communities.
Candice Bobby Untiedt +8 more
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Evolutionary perspective of Big tau structure: 4a exon variants of MAPT
Frontiers in Molecular Neuroscience, 2022 The MAPT gene encoding the microtubule-associated protein tau can generate multiple isoforms by alternative splicing giving rise to proteins which are differentially expressed in specific areas of the nervous system and at different developmental stages.
Itzhak Fischer
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Cell, 1991 Using a sensitive assay for RNA expression, we identified several abnormally spliced transcripts in which exons from a candidate tumor suppressor gene (DCC) were scrambled during the splicing process in vivo. Cloning and sequencing of PCR-amplified segments of the abnormally spliced transcripts showed that exons were joined accurately at consensus ...
J M, Nigro +7 more
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Exon Skipping Is Correlated with Exon Circularization
Journal of Molecular Biology, 2015 Circular RNAs are found in a wide range of organisms and it has been proposed that they perform disparate functions. However, how RNA circularization is connected to alternative splicing remains largely unexplored. Here, we stimulated primary human endothelial cells with tumor necrosis factor α or tumor growth factor β, purified RNA, generated >2.4 ...
Kelly, S +3 more
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Identify alternative splicing events based on position-specific evolutionary conservation. [PDF]
PLoS ONE, 2008 The evolution of eukaryotes is accompanied by the increased complexity of alternative splicing which greatly expands genome information. One of the greatest challenges in the post-genome era is a complete revelation of human transcriptome with ...
Liang Chen, Sika Zheng
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The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer
Frontiers in Molecular Biosciences, 2018 Alternative splicing allows for the expression of multiple RNA and protein isoforms from one gene, making it a major contributor to transcriptome and proteome diversification in eukaryotes.
Ettaib El Marabti, Ihab Younis
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Arquivos de Neuro-Psiquiatria, 2007 Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are caused by mutations in the dystrophin gene. We studied 106 patients with a diagnosis of probable DMD/BMD by analyzing 20 exons of the dystrophin gene in their blood and, in some of
Aline Andrade Freund +5 more
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The emergence of alternative 3' and 5' splice site exons from constitutive exons. [PDF]
PLoS Computational Biology, 2007 Alternative 3' and 5' splice site (ss) events constitute a significant part of all alternative splicing events. These events were also found to be related to several aberrant splicing diseases.
Eli Koren, Galit Lev-Maor, Gil Ast
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Applications in Plant Sciences, 2013 Premise of the study: The genus Ficus (fig trees) comprises ca. 750 species of trees, vines, and stranglers found in tropical forests throughout the world. Fig trees are keystone species in many tropical forests, and their relationship with host-specific
Xiaohong Yao +2 more
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Frontiers in Genetics, 2018 The Tibetan cashmere goat is one of the main goat breeds used by people living in the plateau. It exhibits the distinct phenotypic characteristics observed in lowland goats, allowing them to adapt to the challenging conditions at high altitudes.
Chandar Kumar +9 more
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