Results 191 to 200 of about 419,485 (330)

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

open access: yesAdvanced Science, EarlyView.
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde   +5 more
wiley   +1 more source

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

open access: yesAdvanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang   +20 more
wiley   +1 more source

Impact of Baseline β-Catenin Comutations on Prognosis in EGFR-Mutant Lung Cancer. [PDF]

open access: yesJCO Precis Oncol
Kulhavy J   +22 more
europepmc   +1 more source

Different exon-intron organization at the 5' part of a mouse class I gene is used to generate a novel H-2Kd-related mRNA.

open access: green, 1983
Jean‐Louis Lalanne   +4 more
openalex   +1 more source

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

open access: yesAdvanced Science, EarlyView.
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang   +13 more
wiley   +1 more source

ASCOT identifies key regulators of neuronal subtype-specific splicing [PDF]

open access: yes, 2020
Blackshaw, Seth   +12 more
core   +1 more source

Isolation and characterization of a human collagen a l(I)-like gene from a cosmid library [PDF]

open access: yes, 1982
Cheah, Kathry S. E.   +5 more
core   +1 more source

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