Results 221 to 230 of about 419,485 (330)

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

Advanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang, Xiaofei Wang, Chengli Liu, Kaixuan He, Xiu‐Li Hou, Haofei Luo, Shuaibin Zhang, Changqing You, Yajun Jia, Fuqiang Wang, Xianwei Song, Guodao Liu, Xian Deng, Xiaofeng Cao   +13 more
wiley   +1 more source

Marsupial Ig genomics revisited and the potential role of retroelements in the limited number of heavy chain isotypes. [PDF]

BMC Biol
Sampson JM, Mikolajova KJ, Zimmerly KM, Miller RD.   +3 more
europepmc   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Long-read RNA sequencing unveils a novel cryptic exon in MNAT1 along with its full-length transcript structure in TDP-43 proteinopathy. [PDF]

Commun Biol
Tanaka Y, Sunamura N, Kajitani R, Ikeguchi M, Kunimoto R.   +4 more
europepmc   +1 more source

Deletion of exon 8 causes glycosylasparaginase deficiency in an African American aspartylglucosaminuria (AGU) patient [PDF]

, 1991
Krishna J. Fisher, Nathan N. Aronson
openalex   +1 more source

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

Advanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao, Yi Wu, Haiyang Wang, Chenchun Zhang, Ying Zhu, Yan Jiang, Changyou Jiang, Qiumin Le, Xing Liu, Lan Ma, Feifei Wang   +10 more
wiley   +1 more source

The power of coalescent methods for inferring recent and ancient gene flow in endangered Bactrian camels. [PDF]

Proc Natl Acad Sci U S A
Zhu T, Wang Z, Yang Z.
europepmc   +1 more source

Alternative splicing of a previously unidentified CFTR exon introduces an in‐frame stop codon 5' of the R region [PDF]

, 1993
Carlos A. Melo, Cristina Helena dos Reis Serra, Violeta Stoyanova, Cristina Aguzzoli, D. Faraguna, Anna Tamanini, Giorgio Berton, Giulio Cabrini, Francisco E. Baralle   +8 more
openalex   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC). [PDF]

Front Oncol
Lv JL, Ma R, Ren YS, Liang QY, Zhang HM, Dong GC, Li J.   +6 more
europepmc   +1 more source