Results 231 to 240 of about 586,929 (366)

OrthoMaM v8: a database of orthologous exons and coding sequences for comparative genomics in mammals.

Molecular biology and evolution, 2014
E. Douzery, Céline Scornavacca, J. Romiguier, K. Belkhir, N. Galtier, Frédéric Delsuc, Vincent Ranwez   +6 more
semanticscholar   +1 more source

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer

, 2008
Minh D. To, Christine E. Wong, Anthony N. Karnezis, Reyno Del Rosario, Roberto Di Lauro, Allan Balmain   +5 more
openalex   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

The Spectrum of <i>NOTCH3</i> Variants in an Australian CADASIL Cohort. [PDF]

Genes (Basel)
Guyler SK, Tsai J, Maksemous N, Smith RA, Sutherland HG, Harvey E, Duggins A, Griffiths LR.   +7 more
europepmc   +1 more source

Association Of Initial Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Treatment And EGFR Exon 19 Deletion With Frequency Of The T790M Mutation In Non-Small Cell Lung Cancer Patients After Resistance To First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

, 2019
Wenjing Gao, Jie He, Jin SD, Xu J, Yu TF, Wei Wang, Qing Zhu, Dai H, Hongyan Wu, Liu Yq, Y-q Shu, Guo RH   +11 more
openalex   +1 more source

Identification of antiviral roles for the exon–junction complex and nonsense-mediated decay in flaviviral infection

, 2019
Minghua Li, Jeffrey R. Johnson, Billy Truong, Grace Kim, Nathan L. Weinbren, Mark Dittmar, Priya S. Shah, John Von Dollen, Billy W. Newton, Gwendolyn Μ. Jang, Nevan J. Krogan, Sara Cherry, Holly Ramage   +12 more
openalex   +2 more sources

<p>Exon Coverage Variations Between Cancer Tissues and Adjacent Non-Cancerous Tissues are Prognostic Factors in Gastric Cancer</p>

, 2020
Xuan Pan, Yajing Wang, Chenchen Li, Zhaofei Zhou, Yuejiao Zhong, Jifeng Feng, Jianwei Lu   +6 more
openalex   +2 more sources

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

A subclass of small RNAs is encoded by exons of protein-coding genes. [PDF]

BMC Genomics
Chang T, Hancks DC.
europepmc   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source