Results 271 to 280 of about 586,929 (366)

An overview of insights and updates on TTN mutations in cardiomyopathies. [PDF]

Front Pharmacol
Saha S, Temaj G, Telkoparan-Akillilar P, Chichiarelli S, Saso L.   +4 more
europepmc   +1 more source

A single-base deletion in exon 2 of Hd1 delineates monogenic recessive photoperiod insensitivity in aromatic Joha rice: a novel allele for seasonal adaptability

Bodeddula Jayashankar reddy, Shreekant Baradkar, Tamma V. S. S. Manogna, Dibosh Bordoloi, Subhash C. Bihani, Nagendra Sarma Barua, Akhil Ranjan Baruah, Bikram Das, Suvendu Mondal, Debojit Sarma   +9 more
openalex   +1 more source

PUS7-dependent Ψ reshapes specific synaptic gene exons to facilitate fear extinction memory formation [PDF]

Rong Liu, Yuhan Dong, Zhipeng Gao, Jichun Shi, Ziyue Xu, Junhui Liu, Gaomeng Luo, Shengda Ye, Feiyang Zhang, Hongyu Xu, Xiang Li, Sha Liu, Wei Wei   +12 more
openalex   +1 more source

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

Advanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie, Zhichao Gao, Xin Liu, Shiyi Zhang, Yuhan Wang, Jia Gao, Ping Qi, Lu Zhang, Jiawei Zhao, Tian Xiong, Teng Huang, Jia Song, Qilin Yu, Shu Zhang, Yanjun Liu, Ping Yang, Maryam S. Al‐Motawa, Quan Gong, Junfeng Dong, Hao Yin, Fei Sun, Shiwei Liu, Cong‐Yi Wang   +22 more
wiley   +1 more source

mRNA initiation and termination are spatially coordinated. [PDF]

Science
Calvo-Roitberg E, Carroll CL, Kim G, Sanabria V, Venev SV, Mick ST, Paquette JD, Uriostegui-Arcos M, Dekker J, Fiszbein A, Pai AA.   +10 more
europepmc   +1 more source

Association of intron microsatellite status and exon mutational profiles of TP53 in human colorectal cancer

, 2019
Xin Liu, Dandan Feng, Xueyun Huo, Xiaoqin Xiao, Zhenwen Chen   +4 more
openalex   +2 more sources

Dysregulation of CircZNF79(5) Modulates YBX1 Stability and Selective Autophagy to Drive Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
In HCC, circZNF79(5) binds to YBX1 and functions as an oncogene, recruits BRCC36 to remove K63‐linked ubiquitin chains to stabilize YBX1 protein, and promotes HCC progression via the HIF‐1 signaling pathway. Conversely, circZNF79(5) silencing activates the AMPK/mTOR pathway, inducing p62‐mediated selective autophagic degradation of YBX1.
Xueqiang Guo, Lingling Xi, Yukun Liu, Wenbao Lv, Tianzi Li, Andong Ju, Zhenlin Fan, Yaping Shen, Zhuang Qian, Weiyun Wang, Zhuo Liang, Wenjuan Song, Kaiwen Chang, Shuangping Ma, Junhe Zhang, Tao Han, Kun You, Cunshuan Xu, Lei Wang, Weisheng Guo, Wenjie Ren   +20 more
wiley   +1 more source

ASCOT identifies key regulators of neuronal subtype-specific splicing [PDF]

, 2020
Blackshaw, Seth, Charles, Rone, Clark, Brian S., Ghosh, Devlina, Jiang, Lizhi, Langmead, Ben, Leavey, Patrick J., Ling, Jonathan P., Nellore, Abhinav, Pang, Bo, Santiago, Clayton P., Venkataraman, Anand, Wilks, Christopher   +12 more
core   +1 more source

Enhanced detection and characterization of germline structural variants in cancer predisposition genes via genome sequencing. [PDF]

Genet Med Open
Kargaran PK, Ding Q, Choate LA, Sellers HL, Stein MI, Moyers BA, Basu S, Tandale PP, Setlem R, Bishop MF, Holdren MA, Urban RM, Gupta S, Shen W.   +13 more
europepmc   +1 more source

Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons.

Journal of Molecular Cell Biology, 2012
Zhenxun Wang, D. Chatterjee, H. Y. Jeon, Martin Akerman, M. V. Vander Heiden, L. Cantley, A. Krainer   +6 more
semanticscholar   +1 more source