Results 281 to 290 of about 419,485 (330)

Co‐Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement

Advanced Science, EarlyView.
This study finds that large‐fruited tomatoes accumulate less cadmium (Cd) compared to wild tomatoes and cherry tomatoes. This is because, during the improvement process of tomato, the low‐Cd allele LCT1A and the large fruit allele fw3.2T are closely linked, leading to a co‐selection event.
Xingyu Zhang, Mei Qing, Haobo Xu, Jinbao Tao, Fangman Li, Pingfei Ge, Yang Yang, Wenqian Wang, Yongen Lu, Donald Grierson, Zhibiao Ye, Yuyang Zhang   +11 more
wiley   +1 more source

Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat. [PDF]

Front Genome Ed
Singh T, Mamrutha HM, Singh R, Jaiswal JP, Wadhwa Z, Kumar R, Singh O, Ahlawat OP, Tiwari R.   +8 more
europepmc   +1 more source

GmSop20 Functions as a Key Coordinator of the Oil‐To‐Protein Ratio in Soybean Seeds

Advanced Science, EarlyView.
This study investigates the seed oil‐to‐protein ratio as a comprehensive quality metric and identifies GmSop20 as a crucial regulatory gene through forward genetics methodologies. By integrating GmSop20 with superior haplotypes and using gene editing/overexpression, new strategies are provided for precisely tuning the seed oil‐to‐protein ratio, thereby
Haowei Zheng, Xinkang Feng, Longlong Wang, Wentao Shao, Shiyu Guo, Duo Zhao, Jiajia Li, Long Yan, Long Miao, Bincheng Sun, Huihui Gao, Hongmei Qiu, Yu Hu, Linlin Kong, Robert M. Stupar, Ying‐hui Li, Li‐juan Qiu, Xiaobo Wang   +17 more
wiley   +1 more source

Structure and expression of the human gene for the alpha subunit of prolyl 4-hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues.

, 1994
Tarja Helaakoski, Johanna Veijola, Kristina Vuori, Marko Rehn, Louise T. Chow, P Taillon-Miller, Kari I. Kivirikko, Taina Pihlajaniemi   +7 more
openalex   +1 more source

BRD4 Signaling Maintains the Differentiated State of β Cells

Advanced Science, EarlyView.
The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu, Guang Liu, Jia Song, Yujing Sun, Mengmeng Yang, Hualin Liu, Hongkai Zhao, Jiamu Chen, Qincheng Qiao, Siyue Li, Chenglong Yu, Jingru Qu, Ying Zou, Tixiao Wang, Jidong Liu, Lei Zhao, Huihui Tian, Tao Huang, Manna Zhang, Li Chen, Ruxing Zhao, Yuanyuan Du, Xinguo Hou   +22 more
wiley   +1 more source

Profiling of RBM20-Regulated CaMKIIδ Splice Variants Across the Heart, Skeletal Muscle, and Olfactory Bulbs. [PDF]

Genes Cells
Maeda Y, Yamasu Y, Kuroyanagi H.
europepmc   +1 more source

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

, 1991
E. Tischer, R. Mitchell, Thomas G. Hartman, M. Silva, Denis Gospodarowicz, John C. Fiddes, Judith A. Abraham   +6 more
openalex   +1 more source

YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis

Advanced Science, EarlyView.
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li, Xueying Li, Chunhong Liu, Zhenzhi Li, Kaixin Ding, Yuxin Wang, Ning Gu, Liwei Xie, Zheng Chen   +8 more
wiley   +1 more source

<i>PIK3CA</i> Mutations: Are They a Relevant Target in Adult Diffuse Gliomas? [PDF]

Int J Mol Sci
Tomás A, Pojo M.
europepmc   +1 more source

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

Advanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu, Mengxi Xiu, Shijun Yu, Zhiqin Chen, Yandong Li, Yong Gao   +5 more
wiley   +1 more source