Results 41 to 50 of about 586,929 (366)
Premise of the study: The genus Ficus (fig trees) comprises ca. 750 species of trees, vines, and stranglers found in tropical forests throughout the world. Fig trees are keystone species in many tropical forests, and their relationship with host-specific
Xiaohong Yao +2 more
doaj +1 more source
Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons
Circular RNAs (circRNAs) are a relatively new class of RNA molecules, and knowledge about their biogenesis and function is still in its infancy. It was recently shown that alternative splicing underlies the formation of circular RNAs (circRNA) arising ...
Simona Aufiero +8 more
semanticscholar +1 more source
The Tibetan cashmere goat is one of the main goat breeds used by people living in the plateau. It exhibits the distinct phenotypic characteristics observed in lowland goats, allowing them to adapt to the challenging conditions at high altitudes.
Chandar Kumar +9 more
doaj +1 more source
Splicing complexity as a pivotal feature of alternative exons in mammalian species
Background As a significant process of post-transcriptional gene expression regulation in eukaryotic cells, alternative splicing (AS) of exons greatly contributes to the complexity of the transcriptome and indirectly enriches the protein repertoires.
Feiyang Zhao +4 more
doaj +1 more source
SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements [PDF]
Background: Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization), or the element inserts into the exon, leading to a new transcript.
Ast, Gil +4 more
core +3 more sources
Protein Modularity of Alternatively Spliced Exons Is Associated with Tissue-Specific Regulation of Alternative Splicing. [PDF]
Recent comparative genomic analysis of alternative splicing has shown that protein modularity is an important criterion for functional alternative splicing events.
Yi Xing, Christopher J Lee
doaj +2 more sources
Production of mRNA depends critically on the rate of RNA polymerase II (Pol II) elongation. To dissect Pol II dynamics in mouse ES cells, we inhibited Pol II transcription at either initiation or promoter-proximal pause escape with Triptolide or ...
I. Jonkers, Hojoong Kwak, J. Lis
semanticscholar +1 more source
Clinical exome performance for reporting secondary genetic findings. [PDF]
BACKGROUND : Reporting clinically actionable incidental genetic findings in the course of clinical exome testing is recommended by the American College of Medical Genet- ics and Genomics (ACMG).
Clark, P +6 more
core +1 more source
HnRNP L represses cryptic exons
The fidelity of RNA splicing is regulated by a network of splicing enhancers and repressors, although the rules that govern this process are not yet fully understood.
Sean P. McClory +2 more
semanticscholar +1 more source
Comparative component analysis of exons with different splicing frequencies. [PDF]
Transcriptional isoforms are not just random combinations of exons. What has caused exons to be differentially spliced and whether exons with different splicing frequencies are subjected to divergent regulation by potential elements or splicing signals ...
Shiqin Song +5 more
doaj +1 more source

