Results 41 to 50 of about 586,929 (366)

Exon-Primed Intron-Crossing (EPIC) Markers for Evolutionary Studies of Ficus and Other Taxa in the Fig Family (Moraceae)

open access: yesApplications in Plant Sciences, 2013
Premise of the study: The genus Ficus (fig trees) comprises ca. 750 species of trees, vines, and stranglers found in tropical forests throughout the world. Fig trees are keystone species in many tropical forests, and their relationship with host-specific
Xiaohong Yao   +2 more
doaj   +1 more source

Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons

open access: yesRNA: A publication of the RNA Society, 2018
Circular RNAs (circRNAs) are a relatively new class of RNA molecules, and knowledge about their biogenesis and function is still in its infancy. It was recently shown that alternative splicing underlies the formation of circular RNAs (circRNA) arising ...
Simona Aufiero   +8 more
semanticscholar   +1 more source

Sequence Characterization of DSG3 Gene to Know Its Role in High-Altitude Hypoxia Adaptation in the Chinese Cashmere Goat

open access: yesFrontiers in Genetics, 2018
The Tibetan cashmere goat is one of the main goat breeds used by people living in the plateau. It exhibits the distinct phenotypic characteristics observed in lowland goats, allowing them to adapt to the challenging conditions at high altitudes.
Chandar Kumar   +9 more
doaj   +1 more source

Splicing complexity as a pivotal feature of alternative exons in mammalian species

open access: yesBMC Genomics, 2023
Background As a significant process of post-transcriptional gene expression regulation in eukaryotic cells, alternative splicing (AS) of exons greatly contributes to the complexity of the transcriptome and indirectly enriches the protein repertoires.
Feiyang Zhao   +4 more
doaj   +1 more source

SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements [PDF]

open access: yes, 2007
Background: Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization), or the element inserts into the exon, leading to a new transcript.
Ast, Gil   +4 more
core   +3 more sources

Protein Modularity of Alternatively Spliced Exons Is Associated with Tissue-Specific Regulation of Alternative Splicing. [PDF]

open access: yesPLoS Genetics, 2005
Recent comparative genomic analysis of alternative splicing has shown that protein modularity is an important criterion for functional alternative splicing events.
Yi Xing, Christopher J Lee
doaj   +2 more sources

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

open access: yeseLife, 2014
Production of mRNA depends critically on the rate of RNA polymerase II (Pol II) elongation. To dissect Pol II dynamics in mouse ES cells, we inhibited Pol II transcription at either initiation or promoter-proximal pause escape with Triptolide or ...
I. Jonkers, Hojoong Kwak, J. Lis
semanticscholar   +1 more source

Clinical exome performance for reporting secondary genetic findings. [PDF]

open access: yes, 2014
BACKGROUND : Reporting clinically actionable incidental genetic findings in the course of clinical exome testing is recommended by the American College of Medical Genet- ics and Genomics (ACMG).
Clark, P   +6 more
core   +1 more source

HnRNP L represses cryptic exons

open access: yesRNA: A publication of the RNA Society, 2018
The fidelity of RNA splicing is regulated by a network of splicing enhancers and repressors, although the rules that govern this process are not yet fully understood.
Sean P. McClory   +2 more
semanticscholar   +1 more source

Comparative component analysis of exons with different splicing frequencies. [PDF]

open access: yesPLoS ONE, 2009
Transcriptional isoforms are not just random combinations of exons. What has caused exons to be differentially spliced and whether exons with different splicing frequencies are subjected to divergent regulation by potential elements or splicing signals ...
Shiqin Song   +5 more
doaj   +1 more source

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