Results 181 to 190 of about 8,258 (199)

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, Volume 604, Issue 17, Page 7047-7058, 1 September 2026.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Mechanistic decoupling of exonuclease III multifunctionality into AP endonuclease and exonuclease activities at the single-residue level

Nucleic Acids Research, 2022
Bacterial exonuclease III (ExoIII) is a multifunctional enzyme that uses a single active site to perform two conspicuous activities: (i) apurinic/apyrimidinic (AP)-endonuclease and (ii) 3 '-> 5 ' exonuclease activities.
Gwangrog Lee, Jungmin Yoo, Donghun Lee   +2 more
exaly   +2 more sources

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MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

Cancer Cell, 2021
Jerry W Shay, Silvia Siteni, Mingyi Chen   +2 more
exaly  

T5 exonuclease-dependent assembly offers a low-cost method for efficient cloning and site-directed mutagenesis

Nucleic Acids Research, 2019
Yongzhen Xia, Luying Xun, Lichuan Gu
exaly  

Thermostable Bst DNA polymerase I lacks a 3′ → 5′ proofreading exonuclease activity

Genetic Analysis, Techniques and Applications, 1996
Laurie S Moran, Jack S Benner, Huimin Kong   +2 more
exaly  

Structural analysis of Dis3l2, an exosome-independent exonuclease from Schizosaccharomyces pombe

Acta Crystallographica Section D: Biological Crystallography, 2015
Xu Li, Maikun Teng, Liwen Niu
exaly  

Exonuclease combinations reduce noises in 3D genomics technologies

Nucleic Acids Research, 2020
Baoming Qin, Yinghua Huang, Yubo Zhang   +2 more
exaly  

TOE1 acts as a 3′ exonuclease for telomerase RNA and regulates telomere maintenance

Nucleic Acids Research, 2018
Wenbin Ma, Yujing Li
exaly  

Isolation of Exonuclease VIII: The Enzyme Associated with the sbcA Indirect Suppressor

Proceedings of the National Academy of Sciences of the United States of America, 1974
Sidney Kushner, H Nagaishi
exaly  

CCR4, a 3′-5′ poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

EMBO Journal, 2002
Clyde Denis, Yueh-Chin Chiang, Junji Chen   +2 more
exaly