Osteosarcoma in the Skull of a Holstein Heifer [PDF]
A-2-years-old heifer showed a mass on the frontal part of the skull. Cytological analysis displayed pleomorphic, polyedric and fusiform cells with extracellular hyaline material.
Gimeno, Eduardo Juan +2 more
core +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
Variability of systemic and oro-dental phenotype in two families with non-lethal Raine syndrome with FAM20C mutations [PDF]
Background: Raine syndrome (RS) is a rare autosomal recessive bone dysplasia typified by osteosclerosis and dysmorphic facies due to FAM20C mutations. Initially reported as lethal in infancy, survival is possible into adulthood. We describe the molecular
A Linde +61 more
core +2 more sources
Welfare Indicators for Aquaculture Research: Toolboxes for Five Farmed European Fish Species
ABSTRACT Refining approaches to measuring, monitoring and appraising animal welfare in aquaculture research is key to (i) protecting and optimizing it, (ii) documenting the severity of how and when it deviates, and (iii) ensuring good scientific quality, reliable results and reproducibility, amongst other factors.
Chris Noble +50 more
wiley +1 more source
Effect of vitamin D3 in treating hyperthyroidism in patients with graves’ disease
Background Graves’ disease (GD) is an autoimmune disease characterized by hyperthyroidism secondary to circulating autoantibodies. Multiple factors contributed to its etiology, including genetic and environmental factors.
Nermin A Sheriba +6 more
doaj +1 more source
Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis [PDF]
Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis.
Gallimore, A, Lund, VJ, Paun, S
core +1 more source
Clinical manifestations of Florida spot keratopathy in dogs and cats: One hundred cases (2021–2024)
Abstract Purpose This study describes the ocular findings in dogs and cats diagnosed with Florida spot keratopathy (FSK) at a single institution. Methods Affected animals underwent a single comprehensive ophthalmic examination, with no follow‐ups conducted. Data on patient demographics and clinical findings were collected and analyzed. Results Based on
O. Pe'er +4 more
wiley +1 more source
Mélange of orbital lesions – A histomorphologic study of 135 cases
Background: The orbit is an important site for primary and secondary diseases. Various tissue types such as osseous, vascular, neural, muscular, and glandular may be involved with specific pathologies.
Rashi Gupta +4 more
doaj +1 more source
Paradoxical Worsening of Ocular Symptoms after Spontaneous Closure of a Carotid Cavernous Fistula: Case Report [PDF]
We report an interesting case of a spontaneous occlusion of a carotid cavernous fistula (CCF) causing a paradoxical worsening of orbital symptoms. A 59-year-old woman presented to our institution with conjunctival injection, raised intraocular pressures (
Bilyk, MD, Jurij R. +6 more
core +2 more sources
ABSTRACT Objective To describe calvarial hyperostosis syndrome (CHS) as a potential and unusual cause of exophthalmos or epiphora in young dogs. Animals Studied A nine‐month‐old female intact (case 1) and a two‐year‐old male intact Labrador Retriever (case 2). Procedures Patient history, including previous treatments, was documented.
Andrea Steinmetz, Stefan Kohl
wiley +1 more source

