Results 151 to 160 of about 14,025 (272)

Novel mRNA-silencing bodies at the synapse: A never-ending story

open access: yesCommunicative & Integrative Biology, 2016
Several cellular responses depend on translational regulation and in most cases, this involves the formation of cytoplasmic granules that contain repressed mRNAs.
María Gabriela Thomas   +1 more
doaj   +1 more source

Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors [PDF]

open access: yes, 2016
Small non-coding RNAs called piRNAs serve as guides for an adaptable immune system that represses transposable elements in germ cells of Metazoa. In Drosophila the RDC complex, composed of Rhino, Deadlock and Cutoff (Cuff) bind chromatin of dual-strand ...
Aravin, Alexei A.   +13 more
core   +2 more sources

Exoribonuclease-Resistant RNAs Exist within both Coding and Noncoding Subgenomic RNAs

open access: yesmBio, 2018
Many viruses produce protein-coding and noncoding subgenomic RNAs (sgRNAs) that are critical for infection. A recently discovered pathway for viral sgRNA production uses exoribonuclease-resistant RNAs (xrRNAs), discrete folded RNA elements that block the
Anna-Lena Steckelberg   +2 more
doaj   +1 more source

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development [PDF]

open access: yes, 2013
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Bohnsack, Markus T.   +6 more
core   +3 more sources

Regulation of RNA decay and cellular function by 3′-5′ exoribonuclease DIS3L2

open access: yesRNA Biology, 2019
DIS3L2, in which mutations have been linked to Perlman syndrome, is an RNA-binding protein with 3′-5′ exoribonuclease activity. It contains two CSD domains and one S1 domain, all of which are RNA-binding domains, and one RNB domain that is responsible ...
Siyu Luan   +3 more
semanticscholar   +1 more source

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans. [PDF]

open access: yes, 2016
The exosome complex is a major eukaryotic exoribonuclease that requires the SKI complex for its activity in the cytoplasm. In yeast, the Ski7 protein links both complexes, whereas a functional equivalent of the Ski7 has remained unknown in the human ...
Chlebowski, Aleksander   +7 more
core   +1 more source

Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading

open access: yesCell, 2021
Liming Yan   +15 more
semanticscholar   +1 more source

Degradation of unmethylated miRNA/miRNA*s by a DEDDy-type 3′ to 5′ exoribonuclease Atrimmer 2 in Arabidopsis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance The steady-state levels of miRNAs are under sophisticated control to ensure their proper functions such as development and responses to environmental stimuli.
Xiaoyan Wang   +14 more
semanticscholar   +1 more source

Characterisation of the in-vivo miRNA landscape in Drosophila ribonuclease mutants reveals Pacman-mediated regulation of the highly conserved let-7 cluster during apoptotic processes

open access: yesFrontiers in Genetics
The control of gene expression is a fundamental process essential for correct development and to maintain homeostasis. Many post-transcriptional mechanisms exist to maintain the correct levels of each RNA transcript within the cell.
Elisa I. M. Bernard   +4 more
doaj   +1 more source

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