Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome [PDF]
Tamás I. Orbán, Elisa Izaurralde
openalex +1 more source
Bioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes
IFN‐γ‐primed platelets enriched with immunosuppressive ligands (PD‐L1, PD‐L2, BTLA, and Gal‐9) are shown to induce T cell exhaustion and apoptosis, preserving β‐cell function and preventing hyperglycemia progression in type 1 diabetes. IFN‐γ platelets also promote Treg expansion, macrophage polarization, and β‐cell proliferation, offering a promising ...
Yumeng Ma+14 more
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines. The aim of the CDEs is to improve the standardization of experimental designs across a range of epilepsy ...
Erwin A. van Vliet+11 more
wiley +1 more source
Analysis of cellular responses following interaction with extracellular vesicles derived from HEK293T and human adipose derived stem cells. [PDF]
Zhang W, Obuchi S, Teramura Y.
europepmc +1 more source
The Roles of Intersubunit Interactions in Exosome Stability
Antonio M. Estévez+4 more
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Drosophila gene tazman, an orthologue of the yeast exosome component Rrp44p/Dis3, is differentially expressed during development [PDF]
Fátima Cairrão+2 more
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Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang+4 more
wiley +1 more source
Recent Advances in Enhancing the Sensitivity of Biosensors Based on Field Effect Transistors
This paper discusses the methods to enhancing the detection sensitivity of biosensors in three aspects: overcoming the influence of Debye shielding effects, promoting the binding efficiency of analytes and transistor surface, and improving the structures of device.
Yuying Zhou+8 more
wiley +1 more source
Advances in electrochemical biosensors for the detection of tumor-derived exosomes. [PDF]
Chen J, Zhao Z, Zhu H, Li X.
europepmc +1 more source