Results 211 to 220 of about 130,935 (361)

Exosome-dependent Trafficking of HSP70 [PDF]

open access: hybrid, 2005
Graeme I. Lancaster, Mark A. Febbraio
openalex   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

open access: yesAdvanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen   +12 more
wiley   +1 more source

Evolution of glioma exosome research: emerging trends and global collaborations (2005-2025). [PDF]

open access: yesDiscov Oncol
Zeng Y   +7 more
europepmc   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

open access: yesAdvanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu   +5 more
wiley   +1 more source

Recombinant Hydrophobic Polypeptide MBAY Loaded Into SPION-Exosome Realizes Sustained-Release to Improve Type 2 Diabetes Mellitus

open access: yesDrug Design, Development and Therapy
Xinyu Zong,1,2,* Shangying Xiao,3,* Haishan Xia,3 Dan Guo,1 Jiaping Wu,1 Manjiao Zhuang,3 Lei Rao1 1Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, Medical College, Shaoguan ...
Zong X   +6 more
doaj  

Plant-based Exosome Injections for Skin Wound Healing: Experimental Study. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Adel N   +4 more
europepmc   +1 more source

Mast Cell-Derived Exosomes Induce Phenotypic and Functional Maturation of Dendritic Cells and Elicit Specific Immune Responses In Vivo

open access: bronze, 2003
Dimitris Skokos   +7 more
openalex   +1 more source

ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming [PDF]

open access: bronze, 2005
Elodie Ségura   +7 more
openalex   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

open access: yesAdvanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai   +14 more
wiley   +1 more source

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