Results 231 to 240 of about 76,131 (263)
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Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008
Exosomes are small natural membrane vesicles released by a wide variety of cell types into the extracellular compartment by exocytosis. The biological functions of exosomes are only slowly unveiled, but it is clear that they serve to remove unnecessary cellular proteins (e.g., during reticulocyte maturation) and act as intercellular messengers because ...
Hegmans, Joost P J J +2 more
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Exosomes are small natural membrane vesicles released by a wide variety of cell types into the extracellular compartment by exocytosis. The biological functions of exosomes are only slowly unveiled, but it is clear that they serve to remove unnecessary cellular proteins (e.g., during reticulocyte maturation) and act as intercellular messengers because ...
Hegmans, Joost P J J +2 more
+8 more sources
Exosomes and Exosomal microRNAs in Age-associated Stroke
Current Vascular Pharmacology, 2021Aging has been considered to be the most important non-modifiable risk factor for stroke and death. Changes in circulation factors in the systemic environment, cellular senescence and artery hypertension during human ageing have been investigated. Exosomes are nanosize membrane vesicles that can regulate target cell functions via delivering their ...
Xiang, Wang +6 more
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Diabetes/Metabolism Research and Reviews, 2019
SummaryDiabetes is a group of metabolic diseases characterized by elevated blood glucose levels that drive the development of life‐threatening complications. Diabetes results from a situation of insufficient insulin action, either by deficient production of the hormone by the pancreas, or by the development of insulin resistance in peripheral tissues ...
Carlos Castaño +2 more
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SummaryDiabetes is a group of metabolic diseases characterized by elevated blood glucose levels that drive the development of life‐threatening complications. Diabetes results from a situation of insufficient insulin action, either by deficient production of the hormone by the pancreas, or by the development of insulin resistance in peripheral tissues ...
Carlos Castaño +2 more
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Clinica Chimica Acta
Preeclampsia (PE) is a multifactorial pregnancy disorder marked by new-onset hypertension after 20 weeks of gestation, often accompanied by proteinuria or organ dysfunction. Affecting 4-6 % of pregnancies globally, PE remains a leading cause of maternal and fetal morbidity. While its precise etiology is not fully understood, growing evidence implicates
Asma, Vafadar +5 more
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Preeclampsia (PE) is a multifactorial pregnancy disorder marked by new-onset hypertension after 20 weeks of gestation, often accompanied by proteinuria or organ dysfunction. Affecting 4-6 % of pregnancies globally, PE remains a leading cause of maternal and fetal morbidity. While its precise etiology is not fully understood, growing evidence implicates
Asma, Vafadar +5 more
openaire +2 more sources
Transfusion Clinique et Biologique, 2010
Multivesicular endosomes contain membrane vesicles which can be released into the extracellular environment as exosomes. This review describes the role of exosome secretion in the remodeling of the red cell plasma membrane during the last stage of erythropoietic differentiation. Herein, we propose that the exosome biogenesis involves several mechanisms
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Multivesicular endosomes contain membrane vesicles which can be released into the extracellular environment as exosomes. This review describes the role of exosome secretion in the remodeling of the red cell plasma membrane during the last stage of erythropoietic differentiation. Herein, we propose that the exosome biogenesis involves several mechanisms
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Critical Care Medicine, 2017
Objective: Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) tool in the
TERRASINI, NORA, LIONETTI, Vincenzo
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Objective: Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) tool in the
TERRASINI, NORA, LIONETTI, Vincenzo
openaire +2 more sources
The Role of Exosomes and Exosome-derived microRNAs in Atherosclerosis
Current Pharmaceutical Design, 2018Atherosclerosis is the leading cause of death and morbidity throughout industrialized nations, accounting for one-fifth of all deaths globally. Exosomes are bi-lipid membranous vesicles containing protein, lipid and nucleic acid contents that are released from the cells via the endolysosomal pathway.
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2010
Long before the RNA degrading exosome was first described in the yeast Saccharomyces cerevisiae, the use of autoantibodies found in the sera of certain autoimmune patients allowed the identification of a complex of polypeptides which later appeared to be the human exosome.
Staals, R.H.J., Pruijn, G.J.M.
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Long before the RNA degrading exosome was first described in the yeast Saccharomyces cerevisiae, the use of autoantibodies found in the sera of certain autoimmune patients allowed the identification of a complex of polypeptides which later appeared to be the human exosome.
Staals, R.H.J., Pruijn, G.J.M.
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2010
The archaeal exosome is aprotein complex with structural similarities to the eukaryotic exosome and bacterial PNPase. Its catalytic core is formed by alternating Rrp41 and Rrp42 polypeptides, arranged in a hexameric ring. A flexible RNA binding cap composed of the evolutionarily conserved proteins Rrp4 and/or Cs14 is bound at the top of the ring and ...
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The archaeal exosome is aprotein complex with structural similarities to the eukaryotic exosome and bacterial PNPase. Its catalytic core is formed by alternating Rrp41 and Rrp42 polypeptides, arranged in a hexameric ring. A flexible RNA binding cap composed of the evolutionarily conserved proteins Rrp4 and/or Cs14 is bound at the top of the ring and ...
openaire +3 more sources