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Sphingosine-1-phosphate promotes CD8 T cell exhaustion in breast cancer via exosomal transfer of TGFBR2. [PDF]

open access: yesCell Death Dis
Bhoumick A   +8 more
europepmc   +1 more source
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Exosomes

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008
Exosomes are small natural membrane vesicles released by a wide variety of cell types into the extracellular compartment by exocytosis. The biological functions of exosomes are only slowly unveiled, but it is clear that they serve to remove unnecessary cellular proteins (e.g., during reticulocyte maturation) and act as intercellular messengers because ...
Joost P J J, Hegmans   +2 more
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Exosome and exosomal contents in schizophrenia

Journal of Psychiatric Research, 2023
Schizophrenia (SCZ) is a severe mental disorder that affects approximately 1% general population worldwide and poses a considerable burden to society. Despite decades of research, its etiology remains unclear, and diagnosis remains challenging due to its heterogeneous symptoms.
Tingkai, Zhang   +4 more
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Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

Journal of Controlled Release, 2023
Exosomes are endosome-derived nanovesicles involved in cellular communication. They are natural nanocarriers secreted by various cells, making them suitable candidates for diverse drug delivery and therapeutic applications from a material standpoint. They have a phospholipid bilayer decorated with functional molecules and an enclosed parental matrix ...
Jagannath, Mondal   +6 more
openaire   +2 more sources

siRNA Loaded-Exosomes

2021
Exosomes are membrane-bound vesicles (40-100 nm) of endocytic origin released by numerous cell types that act as natural carriers of mRNA, microRNA, and proteins between cells. We developed a new system that uses intravenous injection of modified exosomes for siRNA delivery into the brain.
María, Izco, Lydia, Alvarez-Erviti
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