Results 231 to 240 of about 182,132 (342)

Survival Motor Neuron Protein is Released from Cells in Exosomes: A Potential Biomarker for Spinal Muscular Atrophy [PDF]

open access: gold, 2017
Leslie A. Nash   +11 more
openalex   +1 more source

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu   +11 more
wiley   +1 more source

Role of exosomes in cancer: from diagnosis to therapy. [PDF]

open access: yesDiscov Oncol
Esparvarinha M   +4 more
europepmc   +1 more source

Repairing the retinal ischemic microenvironment with an engineered exosome-loaded dehydroepiandrosterone peptide hydrogel [PDF]

open access: gold
Zhimou Yang   +14 more
openalex   +1 more source

Immunoregulatory Roles of Tumor‐Originated Pericytes Identified by Single‐Cell Analysis in Glioblastoma

open access: yesAdvanced Science, EarlyView.
The origin and functional heterogeneity of pericytes in glioblastoma (GBM) remain unclear. This study identifies tumor‐originated pericytes (T‐PCs) and normal‐originated pericytes as two distinctive populations in human GBM using single‐cell RNA‐sequencing.
Cuiying Chu   +16 more
wiley   +1 more source

Elysee Exosome Versus Cellbooster Lift in Oral Wound Healing. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Adel N   +9 more
europepmc   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

open access: yesAdvanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li   +4 more
wiley   +1 more source

Exosome-Based Drug Delivery: A Next-Generation Platform for Cancer, Infection, Neurological and Immunological Diseases, Gene Therapy and Regenerative Medicine. [PDF]

open access: yesPharmaceutics
Serrano DR   +11 more
europepmc   +1 more source

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