Results 261 to 270 of about 182,132 (342)

Extracellular Vesicle‐Packaged circTAX1BP1 from Cancer‐Associated Fibroblasts Regulates RNA m6A Modification through Lactylation of VIRMA in Colorectal Cancer Cells

Advanced Science, EarlyView.
This study reveals that CAFs‐derived EVs enriched with circTAX1BP1 drive CRLM by promoting VIRMA lactylation and SP1/TGF‐β signaling, creating a positive feedback loop via ITGA11+ myCAFs. Targeting EV‐circTAX1BP1 and TGF‐β disrupts this loop, offering a novel therapeutic strategy for CRLM.
Jia‐nan Tan, Jin‐hao Yu, Dong Hou, Ye‐quan Xie, Dong‐ming Lai, Fang Zheng, Bin Yang, Jin‐tao Zeng, Yang Chen, Shu‐hong Lu, Guang‐yu Zhong, Fang‐hai Han, Sheng‐ning Zhou   +12 more
wiley   +1 more source

Exosome-based therapeutics in bone regeneration: from fundamental biology to clinical translation. [PDF]

Stem Cell Res Ther
Tajafrooz F, Ghofrani S, Sadeghghomi F, El Hadi Chamas A, Rahimi N, Mirakhor A, Hooshiar MH, Raee A.   +7 more
europepmc   +1 more source

Exosomes derived from HBV‑associated liver cancer promote chemoresistance by upregulating chaperone‑mediated autophagy

, 2018
Dian‐Xing Liu, Peng‐Peng Li, Jiapei Guo, Lei‐Lei Li, Bin Guo, Hong‐Bin Jiao, Jinghua Wu, Junmao Chen   +7 more
openalex   +2 more sources

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

Advanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang, Zhaozhou Ren, Haibo Wang, Xing Yang, Yang Song, Jun Liao, Xiaoying Li   +6 more
wiley   +1 more source

Exosomes as Emerging Therapeutic Strategies in Primary Osteoporosis: A Narrative Review. [PDF]

Drug Des Devel Ther
Chen G, Li H, Chen R, Chen G.
europepmc   +1 more source

The exosome: A versatile RNA processing machine [PDF]

, 1998
Carolyn J. Decker
openalex   +1 more source

Aptamer‐Engineered Ellipsometry for Clinical Detection of BALF‐Derived Exosomes: Multi‐Level Engineering for Prognostic Evaluation of Immunotherapy Responses

Advanced Science, EarlyView.
A novel ellipsometry platform functionalized with truncated PD‐L1 aptamers are developed to enable ultrasensitive detection of BALF‐derived exosomes. Through chemical ligand tailoring, mechanical sensing optimization, and tumor‐proximal fluid sampling, the system precisely stratifies ICI responders and non‐responders, offering superior sensitivity and ...
Euna Jeong, Jung Hyun Choi, Minyoung Lee, Jun Hyeok Lim, Seokho Jung, Yeeun Woo, Joo‐young Kim, Jaehyeon Ok, Lucia Kim, Woo‐jin Jeong, Won Chegal, Hyun Mo Cho, Chulhwan Park, Jiyoon Bu, Dong Hyung Kim, Taek Lee   +15 more
wiley   +1 more source

Exosome Therapy for Chronic Wound Healing. [PDF]

Plast Reconstr Surg Glob Open
Basamage L, Ahn HJ, Choi HS, Antonio CR, Alarcão AL, Silva SN, Hohl ZT, Wan J, Yi KH.   +8 more
europepmc   +1 more source

Enhancing Anti‐Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

Advanced Science, EarlyView.
CD19‐293‐EV can switch the CD19 endocytosis pathway from clathrin‐mediated endocytosis to aggregation‐dependent endocytosis, leading to lysosomal degradation of the CD19/EVs complex. Degradation of the EVs leads to impairment in the IFN response and enhancement in EV uptake by target cells, creating a potent feedback cycle.
Zixuan Huang, Chaoqun Lu, Yixin Wang, Huajian Xian, Yuling Zheng, Ting Kang, Rufang Xiang, Shufeng Xie, Minghui Wang, Zeyi Li, Xiaoli Xia, Yaoyifu Yu, Wenjie Zhang, Huijian Zheng, Renyao Pan, Dan Li, Chunjun Zhao, Han Liu   +17 more
wiley   +1 more source

Exosomal biomarkers in leukemia: translational potential and regulatory challenges for precision medicine applications. [PDF]

Front Immunol
Ansarian MA, Fatahichegeni M, Wang Y, Ren J, Zhang T, Wang X.   +5 more
europepmc   +1 more source