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Exosomes in review: A new frontier in CAR-T cell therapies. [PDF]

open access: yesNeoplasia
Wang JS   +3 more
europepmc   +1 more source
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Exosome and exosomal contents in schizophrenia

Journal of Psychiatric Research, 2023
Schizophrenia (SCZ) is a severe mental disorder that affects approximately 1% general population worldwide and poses a considerable burden to society. Despite decades of research, its etiology remains unclear, and diagnosis remains challenging due to its heterogeneous symptoms.
Tingkai, Zhang   +4 more
openaire   +2 more sources

Exosomes

Annual Review of Biochemistry, 2019
Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, nucleic acids, and glycoconjugates. Exosomes contain an array of membrane-associated, high-order oligomeric protein complexes, display pronounced molecular heterogeneity, and are ...
Pegtel, D. Michiel, Gould, Stephen J.
openaire   +3 more sources

Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles.

Annual Review of Cell and Developmental Biology, 2014
In the 1980s, exosomes were described as vesicles of endosomal origin secreted from reticulocytes. Interest increased around these extracellular vesicles, as they appeared to participate in several cellular processes.
Marina Colombo, G. Raposo, C. Théry
semanticscholar   +1 more source

Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

Journal of Controlled Release, 2023
Exosomes are endosome-derived nanovesicles involved in cellular communication. They are natural nanocarriers secreted by various cells, making them suitable candidates for diverse drug delivery and therapeutic applications from a material standpoint. They have a phospholipid bilayer decorated with functional molecules and an enclosed parental matrix ...
Jagannath, Mondal   +6 more
openaire   +2 more sources

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