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2010
The archaeal exosome is aprotein complex with structural similarities to the eukaryotic exosome and bacterial PNPase. Its catalytic core is formed by alternating Rrp41 and Rrp42 polypeptides, arranged in a hexameric ring. A flexible RNA binding cap composed of the evolutionarily conserved proteins Rrp4 and/or Cs14 is bound at the top of the ring and ...
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The archaeal exosome is aprotein complex with structural similarities to the eukaryotic exosome and bacterial PNPase. Its catalytic core is formed by alternating Rrp41 and Rrp42 polypeptides, arranged in a hexameric ring. A flexible RNA binding cap composed of the evolutionarily conserved proteins Rrp4 and/or Cs14 is bound at the top of the ring and ...
openaire +3 more sources
Engineered exosomes from different sources for cancer-targeted therapy
Signal Transduction and Targeted Therapy, 2023exaly
Exosomes: key players in cancer and potential therapeutic strategy
Signal Transduction and Targeted Therapy, 2020Yong-Guang Tao, Yiqun Jiang
exaly
Application of exosomes as liquid biopsy in clinical diagnosis
Signal Transduction and Targeted Therapy, 2020Biting Zhou, Kailun Xu, Xi Zheng
exaly
Clinical and therapeutic relevance of cancer-associated fibroblasts
Nature Reviews Clinical Oncology, 2021Yang Chen +2 more
exaly
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Nature, 2015Sonia A Melo +2 more
exaly
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
Nature, 2017Sushrut Kamerkar +2 more
exaly
Exosomes: composition, biogenesis and function
Nature Reviews Immunology, 2002Clotilde Théry +2 more
exaly

