Results 171 to 180 of about 17,996 (227)

Exotoxins of Pseudomonas aeruginosa. II. Concentration, Purification, and Characterization of Exotoxin A

Journal of Infectious Diseases, 1973
Exotoxin A of Pseudomonas aeruginosa (PA-103) could be concentrated readily by precipitation with zinc acetate and ammonium sulfate. The toxin was purified by column chromatography with use of DEAE-cellulose and Sephadex G-200. The final product contained about 8,000 mouse LD,,0/mg of protein.
P V, Liu, S, Yoshii, H, Hsieh
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Pseudomonas exotoxin — Immunotoxins

1988
Monoclonal antibodies can be coupled with PE to make very potent ITs. Two of these ITs (PE-HB21 and OVB-3-PE) have been shown to have antitumor activity in a nude mouse model of ovarian cancer. PE ITs are at least 10-fold more active than the corresponding RTA IT.
D J, FitzGerald, M C, Willingham, I, Pastan   +2 more
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Bacterial exotoxins

The Pediatric Infectious Disease Journal, 1989
Article de synthese suyr la biochimie des exotoxines bacteriennes: classification, structure ...
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Characterization of Exotoxin of Pseudomonas aeruginosa

Journal of Infectious Diseases, 1974
Abstract : Heat-labile exotoxin of Pseudomonas aeruginosa has been purified and concentrated. Studies in mice have shown that the toxin affects protein synthesis in the liver within 3 hr of administration, whereas inhibition of protein synthesis in other organs occurs only during terminal stages.
O R, Pavlovskis, L T, Callahan, R D, Meyer   +2 more
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Levodopa – an exotoxin or a therapeutic drug?

Journal of Neurology, 2000
Auto-oxidation of levodopa generates toxic metabolites, such as free radicals, semiquinones and quinones. In vitro, levodopa is a powerful toxin that is lethal to cultures of neurones. This raises the concern that levodopa may also be toxic in vivo, and that chronic treatment with levodopa could induce further damage to nigrostriatal neurones in ...
E, Melamed, D, Offen, A, Shirvan, I, Ziv
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Septic Cardiomyopathy and Bacterial Exotoxins

Critical Care Medicine, 2018
Septic cardiopathy and bacterial exotoxins (letter)
Monticelli, Jacopo, Di Bella, Stefano, Di Masi, Alessandra, Zennaro, Cristina, Tonon, Federica, Luzzati, Roberto   +5 more
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