Results 31 to 40 of about 20,276 (258)

Susceptibility of hamsters to clostridium difficile isolates of differing toxinotype [PDF]

, 2013
Clostridium difficile is the most commonly associated cause of antibiotic associated disease (AAD), which caused ~21,000 cases of AAD in 2011 in the U.K. alone.
A Buckley, Anthony M. Buckley, B Elliott, C Rousseau, C Schwan, D Drudy, D Goulding, D Lyras, Denise Candlish, DM Guerrero, F Miyajima, Gillian R. Douce, H Huang, H Kim, H Kim, I Duerden, I Vesteinsdottir, J Andrews, J Kim, J Ng, J Pépin, J Wang, Janice Spencer, JG Bartlett, JM Lanis, June J. Irvine, JW Marsh, LA Petrella, Lindsay M. Maclellan, LJ Deakin, M Arvand, M He, M Merrigan, M Rupnik, MH Wilcox, MH Wilcox, Michel R. Popoff, MM Nerandzic, MSM Brouwer, N Razaq, N Stoesser, P Vohra, R Stabler, R Stabler, S Kamiya, S Kuehne, SA Villano, SP Sambol, SP Sambol, ST Cartman, TS Steiner, V Braun, V Casas, Y Ogura   +53 more
core   +7 more sources

Spatiotemporal Regulation of Vibrio Exotoxins by HlyU and Other Transcriptional Regulators

Toxins, 2020
After invading a host, bacterial pathogens secrete diverse protein toxins to disrupt host defense systems. To ensure successful infection, however, pathogens must precisely regulate the expression of those exotoxins because uncontrolled toxin production ...
Byoung Sik Kim
doaj   +1 more source

The burden of clostridium difficile infection in patients with liver cirrhosis [PDF]

, 2019
Clostridium Difficile Infection (CDI) has registered a dramatically increasing incidence in the general population over the past decades. Nowadays, Clostridium Difficile is the leading cause of hospital-acquired diarrhea in Europe and North America ...
Dumitru, Andrada, Emanuela, Popoiag R, Micu, Sergiu I, Moraru, Despina, Musat, Marilena, Preda, Gabriel   +5 more
core   +2 more sources

Toxic shock syndrome with a cytokine storm caused by Staphylococcus simulans: a case report

BMC Infectious Diseases, 2021
Background Exotoxins secreted from Staphylococcus aureus or Streptococcus pyogenes act as superantigens that induce systemic release of inflammatory cytokines and are a common cause of toxic shock syndrome (TSS). However, little is known about TSS caused
Ken Goda, Tsuneaki Kenzaka, Masahiko Hoshijima, Akihiro Yachie, Hozuka Akita   +4 more
doaj   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Exotoxins ofStaphylococcus aureus [PDF]

Clinical Microbiology Reviews, 2000
SUMMARYThis article reviews the literature regarding the structure and function of two types of exotoxins expressed by Staphylococcus aureus, pyrogenic toxin superantigens (PTSAgs) and hemolysins. The molecular basis of PTSAg toxicity is presented in the context of two diseases known to be caused by these exotoxins: toxic shock syndrome and ...
M M, Dinges, P M, Orwin, P M, Schlievert
openaire   +2 more sources

Screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis. [PDF]

PLoS ONE, 2010
BACKGROUND: Staphylococcus aureus secretes numerous exotoxins which may exhibit superantigenic properties. Whereas the virulence of several of them is well documented, their exact biological effects are not fully understood.
Frédéric Heymans, Adrien Fischer, Nicholas W Stow, Myriam Girard, Zacharias Vourexakis, Antoine Des Courtis, Gesuele Renzi, Elzbieta Huggler, Stefan Vlaminck, Pierre Bonfils, Ranko Mladina, Valerie Lund, Jacques Schrenzel, Patrice François, Jean Silvain Lacroix   +14 more
doaj   +1 more source

Toxin-neutralizing antibodies protect against Clostridium perfringens-induced necrosis in an intestinal loop model for bovine necrohemorrhagic enteritis [PDF]

, 2016
Background: Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens type A. Due to the rapid progress and fatal outcome of the disease, vaccination would be of high value. In this study, C.
Deprez, Piet, Ducatelle, Richard, Goossens, Evy, Haesebrouck, Freddy, Pardon, Bart, Rodrigo, Diego, Schauvliege, Stijn, Timbermont, Leen, Valgaeren, Bonnie, Van Immerseel, Filip, Verherstraeten, Stefanie   +10 more
core   +2 more sources

Effect of Sub-Minimum Inhibitory Concentrations of Tyrosol and EDTA on Quorum Sensing and Virulence of Pseudomonas aeruginosa

Infection and Drug Resistance, 2020
Shaymaa H Abdel-Rhman,1,2 Dina E Rizk,1 Eman S Abdelmegeed1 1Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; 2Department of Pharmaceutics and Pharmaceutical Biotechnology, Faculty of Pharmacy, Taibah ...
Abdel-Rhman SH, Rizk DE, Abdelmegeed ES
doaj  

Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3 - Implications for the evolution of staphylococcal pathogenicity islands [PDF]

, 2002
We describe the complete sequence of the 15.9-kb staphylococcal pathogenicity island 3 encoding staphylococcal enterotoxin serotypes B, K, and Q. The island, which meets the generally accepted definition of pathogenicity islands, contains 24 open reading
Kapur, Vivek, McCormick, John K., Orwin, Paul M., Paustian, Michael L., Schlievert, Patrick M., Yarwood, Jeremy M.   +5 more
core