Results 21 to 30 of about 10,497 (180)
Staphylococcus aureus Exotoxins and Their Detection in the Dairy Industry and Mastitis
Toxins, 2020 Staphylococcus aureus constitutes a major food-borne pathogen, as well as one of the main causative agents of mastitis in dairy ruminants. This pathogen can produce a variety of extracellular toxins; these include the shock syndrome toxin 1 (TSST-1 ...
Ana G. Abril +6 more
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Cells, 2022 The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their ...
Hervé Besançon +4 more
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Subinhibitory concentrations of perilla oil affect the expression of secreted virulence factor genes in Staphylococcus aureus. [PDF]
PLoS ONE, 2011 BACKGROUND: The pathogenicity of staphylococcus aureus is dependent largely upon its ability to secrete a number of virulence factors, therefore, anti-virulence strategy to combat S. aureus-mediated infections is now gaining great interest.
Jiazhang Qiu +10 more
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Intrinsic Toxin-Derived Peptides Destabilize and Inactivate
mBio, 2017 Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial toxins, TcdA and TcdB.
Jason L. Larabee +3 more
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Staphylococcal and Streptococcal Superantigen Exotoxins [PDF]
Clinical Microbiology Reviews, 2013 SUMMARYThis review begins with a discussion of the large family ofStaphylococcus aureusand beta-hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and immunobiological perspectives. With this as background, the review then discusses the major known and possible human disease associations with superantigens, including ...
Adam R, Spaulding +5 more
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Tailored liposomal nanotraps for the treatment of Streptococcal infections
Journal of Nanobiotechnology, 2021 Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of pathogen clearance
Hervé Besançon +9 more
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Spatiotemporal Regulation of Vibrio Exotoxins by HlyU and Other Transcriptional Regulators
Toxins, 2020 After invading a host, bacterial pathogens secrete diverse protein toxins to disrupt host defense systems. To ensure successful infection, however, pathogens must precisely regulate the expression of those exotoxins because uncontrolled toxin production ...
Byoung Sik Kim
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Toxic shock syndrome with a cytokine storm caused by Staphylococcus simulans: a case report
BMC Infectious Diseases, 2021 Background Exotoxins secreted from Staphylococcus aureus or Streptococcus pyogenes act as superantigens that induce systemic release of inflammatory cytokines and are a common cause of toxic shock syndrome (TSS). However, little is known about TSS caused
Ken Goda +4 more
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Screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis. [PDF]
PLoS ONE, 2010 BACKGROUND: Staphylococcus aureus secretes numerous exotoxins which may exhibit superantigenic properties. Whereas the virulence of several of them is well documented, their exact biological effects are not fully understood.
Frédéric Heymans +14 more
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Infection and Drug Resistance, 2020 Shaymaa H Abdel-Rhman,1,2 Dina E Rizk,1 Eman S Abdelmegeed1 1Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; 2Department of Pharmaceutics and Pharmaceutical Biotechnology, Faculty of Pharmacy, Taibah ...
Abdel-Rhman SH, Rizk DE, Abdelmegeed ES
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