Results 21 to 30 of about 17,996 (227)
Molecular Mechanisms of Mast Cell Activation by Cholesterol-Dependent Cytolysins
Frontiers in Immunology, 2021 Mast cells are potent immune sensors of the tissue microenvironment. Within seconds of activation, they release various preformed biologically active products and initiate the process of de novo synthesis of cytokines, chemokines, and other inflammatory ...
Lubica Draberova +2 more
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Bacterial Exotoxins: General Characteristics and Mode of Action [PDF]
مجلة جامعة كركوك للعلوم الزراعيةThe idea of the harmful effects of pathogenic bacteria via toxin production has existed since ancient times. In 1872, Klebs hypothesized that "sepsins" were responsible for the formation of toxins produced by staphylococci, although he was unable to ...
Mustafa Omar
doaj +1 more source
Staphylococcus aureus Exotoxins and Their Detection in the Dairy Industry and Mastitis
Toxins, 2020 Staphylococcus aureus constitutes a major food-borne pathogen, as well as one of the main causative agents of mastitis in dairy ruminants. This pathogen can produce a variety of extracellular toxins; these include the shock syndrome toxin 1 (TSST-1 ...
Ana G. Abril +6 more
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Cells, 2022 The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their ...
Hervé Besançon +4 more
doaj +1 more source
Subinhibitory concentrations of perilla oil affect the expression of secreted virulence factor genes in Staphylococcus aureus. [PDF]
PLoS ONE, 2011 BACKGROUND: The pathogenicity of staphylococcus aureus is dependent largely upon its ability to secrete a number of virulence factors, therefore, anti-virulence strategy to combat S. aureus-mediated infections is now gaining great interest.
Jiazhang Qiu +10 more
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Intrinsic Toxin-Derived Peptides Destabilize and Inactivate
mBio, 2017 Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial toxins, TcdA and TcdB.
Jason L. Larabee +3 more
doaj +1 more source
Staphylococcal and Streptococcal Superantigen Exotoxins [PDF]
Clinical Microbiology Reviews, 2013 SUMMARYThis review begins with a discussion of the large family ofStaphylococcus aureusand beta-hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and immunobiological perspectives. With this as background, the review then discusses the major known and possible human disease associations with superantigens, including ...
Adam R, Spaulding +5 more
openaire +2 more sources
Toxin Production by Aeromonas sobria in Natural Environments: River Water vs. Seawater [PDF]
, 2008 Aeromonas are water-borne pathogens. They are halotolerant, which means that they can survive in environments whose salt content corresponds to that of seawater (3.0% NaCl).
Ansaruzzaman, Mohammad +6 more
core +1 more source
The burden of clostridium difficile infection in patients with liver cirrhosis [PDF]
, 2019 Clostridium Difficile Infection (CDI) has registered a dramatically increasing incidence in the general population over the past decades. Nowadays, Clostridium Difficile is the leading cause of hospital-acquired diarrhea in Europe and North America ...
Dumitru, Andrada +5 more
core +2 more sources
Tailored liposomal nanotraps for the treatment of Streptococcal infections
Journal of Nanobiotechnology, 2021 Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of pathogen clearance
Hervé Besançon +9 more
doaj +1 more source