The binding of botulinum neurotoxins to different peripheral neurons [PDF]
, 2017 Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
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Spatiotemporal Regulation of Vibrio Exotoxins by HlyU and Other Transcriptional Regulators
Toxins, 2020 After invading a host, bacterial pathogens secrete diverse protein toxins to disrupt host defense systems. To ensure successful infection, however, pathogens must precisely regulate the expression of those exotoxins because uncontrolled toxin production ...
Byoung Sik Kim
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Comparison of ferment sugars, produce hemolysis and measuring growth in methicillin-resistant and methicillin-sensitive Staphylococcus aureus isolates from inpatients and healthcare workers in Gorgan Hospitals, North of Iran [PDF]
, 2013 The mec A gene in Staphylococcus aureus leads to production of new penicillin-binding protein called PBP2a.This change may follow some changes in other phenotypes.
Amini, A. +7 more
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Toxic shock syndrome with a cytokine storm caused by Staphylococcus simulans: a case report
BMC Infectious Diseases, 2021 Background Exotoxins secreted from Staphylococcus aureus or Streptococcus pyogenes act as superantigens that induce systemic release of inflammatory cytokines and are a common cause of toxic shock syndrome (TSS). However, little is known about TSS caused
Ken Goda +4 more
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Susceptibility of hamsters to clostridium difficile isolates of differing toxinotype [PDF]
, 2013 Clostridium difficile is the most commonly associated cause of antibiotic associated disease (AAD), which caused ~21,000 cases of AAD in 2011 in the U.K. alone.
A Buckley +53 more
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Exotoxins ofStaphylococcus aureus [PDF]
Clinical Microbiology Reviews, 2000 SUMMARYThis article reviews the literature regarding the structure and function of two types of exotoxins expressed by Staphylococcus aureus, pyrogenic toxin superantigens (PTSAgs) and hemolysins. The molecular basis of PTSAg toxicity is presented in the context of two diseases known to be caused by these exotoxins: toxic shock syndrome and ...
M M, Dinges, P M, Orwin, P M, Schlievert
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Detection of Exotoxins and Antimicrobial Susceptibility Pattern in Clinical Pseudomonas Aeruginosa Isolates [PDF]
, 2017 Background: Pseudomonas aeruginosa is a common opportunistic pathogen that causes nosocomial infection in immunocompromised patients. Among different virulence factors, the type III secretion system (TTSS) is an important agent in virulence and ...
Deris, Fatemeh. +4 more
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The exotoxins ofCorynebacterium ulcerans [PDF]
Journal of Hygiene, 1982 SummaryThe exotoxins produced by ten strains ofC. ulcerans(two human, six bovine and two equine) have been studied. On the criteria of toxin–antitoxin neutralisation and immunoprecipitation tests using highly specific diphtheria andC. ovisantitoxins with crude toxic filtrates, (NH4)2SO4concentrates, and partially purified chromatographic preparations ...
H R, Carne, E O, Onon
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Infection and Drug Resistance, 2020 Shaymaa H Abdel-Rhman,1,2 Dina E Rizk,1 Eman S Abdelmegeed1 1Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; 2Department of Pharmaceutics and Pharmaceutical Biotechnology, Faculty of Pharmacy, Taibah ...
Abdel-Rhman SH, Rizk DE, Abdelmegeed ES
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Screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis. [PDF]
PLoS ONE, 2010 BACKGROUND: Staphylococcus aureus secretes numerous exotoxins which may exhibit superantigenic properties. Whereas the virulence of several of them is well documented, their exact biological effects are not fully understood.
Frédéric Heymans +14 more
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