Results 121 to 130 of about 109,706 (265)

Valeurs comparées du BCG vivant ou tué et du bacille de Koch trypsiné dans l'immunisation des zébus contre la tuberculose [PDF]

open access: yes, 1975
L'inoculation de bacilles tuberculeux virulents par voie intraveineuse à 40 bovins témoins et 70 vaccinés a démontré que trois vaccins protégeaient dans des proportions à peu près équivalentes: 1. Le BCG vivant (100 mg, voie sous cutanée): 17,14 à 28,5 p.
Blancou, Jean, Cheneau, Yves
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Pro-Angiogenic Effects of Canine Platelet-Rich Plasma: In Vitro and In Vivo Evidence

open access: yesAnimals
Platelet-rich plasma (PRP) is widely applied in veterinary regenerative medicine due to its rich composition of growth factors that promote tissue repair.
Seong-Won An, Young-Sam Kwon
doaj   +1 more source

Le croisement Brahman à Madagascar (série de photographies) [PDF]

open access: yes, 1969
Le lecteur trouvera ci-après une série de photographies concernant l'article "Le croisement Brahman à Madagascar" paru dans le tome 21, no 4 pages 519-61 qui, pour des raisons techniques, n'ont pu être publiées en même temps que le texte.
Capitaine, Paul   +4 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Résultats de l'expérimentation de l'ivermectine (Ivomec R) sur les parasites du dromadaire au Niger [PDF]

open access: yes, 1986
Un essai thérapeutique avec l'ivermectine à la dose de 200 ?g/kg/vif a été mené au Niger sur 10 dromadaires (5 témoins, 5 traités) naturellement infestés par des nématodes du genre Haemonchus, Impalaia, Oesophagostomum, Trichostrongylus.
Robin, Bernard, Tager-Kagan, Pierre
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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