Results 51 to 60 of about 114,889,184 (267)

Multimodality Imaging of Silica and Silicon Materials In Vivo [PDF]

, 2018
Recent progress in the development of silica? and silicon?based multimodality imaging nanoprobes has advanced their use in image?guided drug delivery, and the development of novel systems for nanotheranostic and diagnostic applications.
Mirkka P. Sarparanta, M., Rosenholm Jessica, P., Sarparanta Mirkka, Jessica M. Rosenholm, Anu J. Airaksinen, Didem Şen Karaman, Şen, Karaman Didem, J., Airaksinen Anu   +7 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Real-Time Wireless Platform for In Vivo Monitoring of Bone Regeneration

Sensors, 2020
For the monitoring of bone regeneration processes, the instrumentation of the fixation is an increasingly common technique to indirectly measure the evolution of bone formation instead of ex vivo measurements or traditional in vivo techniques, such as X ...
Pablo Blázquez-Carmona, Manuel Sanchez-Raya, Juan Mora-Macías, Juan Antonio Gómez-Galán, Jaime Domínguez, Esther Reina-Romo   +5 more
doaj   +1 more source

Prenatal transmission of scrapie in sheep and goats: A case study for veterinary public health [PDF]

Open Veterinary Journal, 2016
Unsettled knowledge as to whether scrapie transmits prenatally in sheep and goats and transmits by semen and preimplantation embryos has a potential to compromise measures for controlling, preventing and eliminating the disease.
D.B. Adams
doaj   +1 more source

Brain Tissue Conductivity Measurements with MR-Electrical Properties Tomography: An In Vivo Study [PDF]

, 2021
First in vivo brain conductivity reconstructions using Helmholtz MR-Electrical Properties Tomography (MR-EPT) have been published. However, a large variation in the reconstructed conductivity values is reported and these values differ from ex vivo ...
Vink, Jord J T, Mandija, Stefano, van den Berg, Cornelis A T, Neggers, Sebastian F W, Petrov, Petar I   +4 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A range finding protocol to support design for transcriptomics experimentation: examples of in-vitro and in-vivo murine UV exposure. [PDF]

PLoS ONE, 2014
In transcriptomics research, design for experimentation by carefully considering biological, technological, practical and statistical aspects is very important, because the experimental design space is essentially limitless.
Oskar Bruning, Wendy Rodenburg, Conny T van Oostrom, Martijs J Jonker, Mark de Jong, Rob J Dekker, Han Rauwerda, Wim A Ensink, Annemieke de Vries, Timo M Breit   +9 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

vivo-project/VIVO: Release vivo-1.14.1

<p><strong>Release vivo 1.14.1</strong><br/>It is recommended that you review the 1.14 Documentation and the VIVO/Vitro READMEs on github before you start.<br/>If you are new to VIVO/Vitro it is suggested that you take ...
Jim Blake, Stefan-Wolff, Brian Caruso, Andrew Woods, Nate Prewitt, William Welling, Don Elsborg, hudajkhan, Ralph O'Flinn, Georgy Litvinov, Alex Viggio, tworrall, Ben, Ted Lawless, Miloš Popović, Arfon Smith, vivo-uab, Jon Corson-Rikert, Steve McKay, Mike Conlon, Dragan Ivanovic, hauschke, Brian Lowe, Stephen V. Williams, Holly Mistlebauer, Michel Héon, Laura Wrubel, Graham Triggs   +27 more
core   +1 more source