Results 91 to 100 of about 501,356 (299)
Meeting the rare earth expanding circle
Access Microbiology, 2019 The increasing demand for rare earth elements (REE) is fuelled by their importance in a green energy future, with the demand for dysprosium predicted to increase by 5 % annually by 2026. Bioleaching approaches are being investigated for the recovery of REE and other precious metals from waste materials, however even 100 % recovery will not be able to ...
Megan Barnett +3 more
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Revista Alicantina de Estudios Ingleses, 2017 The realization of postvocalic /r/ has been frequently examined in both diachronic and synchronic research on world Englishes, showing a multitude of linguistic and extra-linguistic factors to modulate the degree of rhoticity.
Li, Zeyu, Kabak, Barış
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Ergodic theory of generic continuous maps
, 2012 We study the ergodic properties of generic continuous dynamical systems on compact manifolds. As a main result we prove that generic homeomorphisms have convergent Birkhoff averages under continuous observables at Lebesgue almost every point. In spite of
Abdenur, Flávio, Andersson, Martin
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Virtual social media communities and their effects on World Englishes
Journal of Language and Cultural EducationThis paper investigates the impact of social media use and virtual communities on world Englishes. The term world Englishes refers to the different varieties of how English is communicated worldwide. Kachru (1985) described the language’s spread in terms
Almohawes Monera
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Validation in grounded theory: conversation circles as a methodological strategy
Revista Brasileira de EnfermagemObjective: To present the validation of a theoretical model through conversation circles in a qualitative research guided by the Grounded Theory. Method: Study carried out from a thesis developed in a reference hospital in the south region of Brazil ...
Edlamar Kátia Adamy +4 more
doaj +1 more source