Results 171 to 180 of about 1,414,501 (231)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Correlation of Smartphone Screen Time With Resting Respiratory Rate, Head-Neck Alignment, and Chest Expansion Among University Students. [PDF]

Cureus
Tapale VS, Chintamani R.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Medicaid Expansion and Mortality Among Patients With Colorectal Cancer.

JAMA Netw Open
Akinyemi O, Oyebanji O, Oluborode B, Akinwumi B, Ogunyankin F, Hughes K, Fullum T, Chu Q, Nalamati S, Abouljoud M, Nembhard C, Reickert C.   +11 more
europepmc   +1 more source

Erratum to Clonal expansion of alveolar fibroblast progeny drives pulmonary fibrosis in mouse models. [PDF]

J Clin Invest
Molina C, Tsukui T, Khan IS, Ren X, Qiu W, Matthay M, Wolters P, Sheppard D.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A strong and ductile Super Kovar alloy via fully coherent nanoprecipitates. [PDF]

Sci Adv
Yu C, Chen Y, Zhu H, Yang Y, Zhang Y, Gu L, Khmelevskyi S, Kato K, An K, Yu D, Chen Y, Ma X, Yang W, Raabe D, Xing X.   +14 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Finite Element Investigation of the Influence of Strut Diameter on the Mechanical Performance of Balloon-Expandable Biodegradable PLA/PDO Coronary Stents. [PDF]

Polymers (Basel)
Besseghier E, Kettaf FZ, Bouakkaz AO, Djebli A, Benhamena A, Sekban DM, Uzun Yaylacı E, Terzi M, Yaylacı M.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source