Results 161 to 170 of about 1,302,538 (247)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

IntAct-U-ExM enables super-resolution imaging of isoform-specific actin networks across species. [PDF]

PLoS Biol
Dhar A, Dey S, Mullick S, Suman NK, van Zwam MC, Palani Balaji NK, Ghosh A, Nair D, van den Dries K, Gadadhar S, Palani S.   +10 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Biografía

, 2000
Este vídeo trata de la vida de Jeff Bezos el creador de la pagina de Internet mas popular en ventas electrónicas “Amazon”
A y E Televisión Networks
core  

Expanding equality? Institutional differentiation and reform in the access to higher education-the case of quota policies at USP. [PDF]

Front Sociol
de Brito MMA.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Arboles de expansión en optimización de caminos [PDF]

El presente trabajo de investigación se enmarca en el área de la matemática discreta y tiene como propósito profundizar en el estudio teórico de las propiedades matemáticas de caminos en grafos, con énfasis en los árboles de expansión para optimizar ...
Rivero Curi, Pilar
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Análisis del plan de expansión de transmisión

, 2004
Realiza un análisis del plan de expansión de transmisión para el período 2004 - 2013, a través de la evaluación de las condiciones de operación del sistema nacional interconectado, en concordancia con los proyectos propuestos en el plan.
Guerrero López, Daniel Patricio
core  

Urban compactness and Land Use Efficiency in Indochina Capitals: A multi-method spatial assessment (2017-2024). [PDF]

PLoS One
Nguyen TT.
europepmc   +1 more source