Results 141 to 150 of about 1,414,501 (231)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

CAJA 295 - LEGAJO VII - SIGNATURA 10

open access: yes, 1909
Nota remitida por el Servicio Oficial de Expansión Económica del Brasil, a la Biblioteca de la Económica Valenciana, comunicándole el envío de una serie de publicaciones relativas al Brasil.Servicio Oficial de Expansión Económica del Brasil (1909).
Servicio Oficial de Expansión Económica del Brasil
core  

Identifying the principal mechanism of star formation feedback. [PDF]

open access: yesSci Adv
Li C   +29 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Las 500 contra la corrupción

open access: yes
Integridad Corporativa 500 (IC500) es una iniciativa conjunta de Transparencia Mexicana, Mexicanos contra la Corrupción y la Impunidad y la revista Expansión.
Grupo Expansión
core  

Expansión rápida palatina

open access: yes, 1991
RESUMEN: El presente artículo hace una revisión de los antecedentes y de la anatomía del área involucrada. A partir de esto, se discute la elaboración y el manejo clínico de la expansión rápida palatina, diferenciándola de la expansión lenta de los ...
Saldarriaga, Julio Roberto
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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