Results 121 to 130 of about 1,414,501 (231)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Expansión estratégica en la asociación de desarrollo social e integral de la comunidad de Pímbalo dedicada a la producción de queso fresco y mozzarella

open access: yes, 2015
1. Introducción. --2. Planteamiento de la propuesta de trabajo. --3. Marco teórico. --4. Metodología. --5. Resultados. --6. Conclusiones y RecomendacionesBajo el tema ?Expansión estratégica en la asociación de desarrollo social e integral de la comunidad
Guachamín Bustillos, Mónica Cecilia
core  

Aplicación de la teledetección satelital en el estudio de la expansión urbana ciudad de Jaén 2013-2023 [PDF]

open access: yes
La presente investigación tuvo como objetivo aplicar la Teledetección Satelital para determinar la expansión urbana de la ciudad Jaén desde el año 2013 hasta la actualidad.
Nuñez Jaramillo,Abner Izai   +1 more
core   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

En tiempos de extorsión

open access: yes
El Índice IC500, que elaboramos con MCCI y publicamos anualmente en Expansión nos lo recuerda: la empresa que tiene 100 puntos no es la empresa perfecta, sino la que está mejor preparada para ...
Grupo Expansión
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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