Results 131 to 140 of about 1,302,538 (247)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
El presente proyecto analiza el mercado inmobiliario de lujo en Miami, Florida, y propone una estrategia de expansión para la firma Engel & Völkers Miami ante un entorno competitivo y altamente internacionalizado.
Gonzalez Sepulveda, Juan Pablo
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FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Ciclos de negocios en Colombia, 1975-2011
Lecturas de Economía, 2013 Se propone una cronología para los ciclos de negocios de Colombia en la concepción clásica del NBER; esto es, determinando las fechas de picos y valles en la actividad económica sin separar las series utilizadas en sus componentes transitorio y ...
Viviana Alfonso +4 more
doaj
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
[Español] Objetivo: Evaluar tridimensionalmente los efectos de la expansión rápida maxilar sobre la arcada inferior en niños utilizando modelos digitales.
Arianna Gabriela Medina Brito +1 more
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Informe del Proyecto "Expansión del cultivo del albaricoquero en Aragón" (GCP-2016-0021-00)
, 2018 Miembros beneficiarios: Viveros Mariano Soria S.L ; AFRUCCAS ; COSANSEMiembros no beneficiarios: Centro de Investigación y Tecnología Agroalimentaria de Aragón (CITA) (coordinador) ; Agrostock ; Bancal SL ; Centro Transferencia Agroalimentaria (CTA ...
Grupo de Cooperación Expansión del cultivo del albaricoquero en Aragón
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