Results 51 to 60 of about 1,830,949 (244)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Un análisis del comportamiento cíclico de las cooperativas y sociedades laborales españolas y su relación con la actividad económica

open access: yesRevista de Estudios Cooperativos, 2014
Existe un amplio debate acerca del papel que ha jugado y juega la Economía Social en el proceso de desarrollo y de creación de empleo estable. En dicho debate resulta de interés conocer cuáles son las características que definen las fases cíclicas de las
Mercè Sala Ríos   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

El impacto del comercio social en la expansión del mercado de productos de belleza online en la ciudad de Ambato

open access: yesRevista Metropolitana de Ciencias Aplicadas
Este estudio investiga el impacto del comercio social en la expansión del mercado de productos de belleza en línea en Ecuador, con un enfoque en la ciudad de Ambato.
Lorena Elizabeth Flores-Carrillo   +1 more
doaj   +1 more source

Introduction [PDF]

open access: yes, 1998
The costs and benefits of European Imperialism from the conquest of Ceuta, 1415, to the Treaty of Lusaka, 1974.Twelfth International Economic History Congress. Madrid, 1998.Patrick K.
O'Brien, Patrick K.   +1 more
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Theoretical and practical validation tests for a near-field to far-field transformation algorithm using spherical wave expansion [PDF]

open access: yes, 2012
The use of spherical wave expansion of the solution of the wave equation to predict Far-Field values from data measured in the Near-Field region is a well known technique, typically used to perform antenna measurements in compact anechoic chambers ...
Azpúrua Auyanet, Marco Aurelio   +5 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Transformación urbana de la ciudad de Bogotá, 1990-2010: efecto espacial de la liberalización del comercio / Urban transformation of the Bogotá city, 1990-2010: spatial effect of the liberalization of commerce

open access: yesPerspectiva Geográfica, 2011
Se analiza en el artículo la transformación urbana de Bogotá en los últimos 20 años, adelantada en el marco de los procesos de globalización y liberalización del comercio.
Jorge Alessandri Romero Novoa
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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