Results 81 to 90 of about 34,807 (305)

Multiscale expansion and integrability properties of the lattice potential KdV equation

, 2008
We apply the discrete multiscale expansion to the Lax pair and to the first few symmetries of the lattice potential Korteweg-de Vries equation. From these calculations we show that, like the lowest order secularity conditions give a nonlinear Schrödinger
Decio Levi, Petrera, Matteo, Matteo Petrera, Scimiterna, Christian, Heredero RH, Petrera M, Levi, Decio, Rafael Hernandez Heredero, Scimiterna C., Hernández Heredero, Rafael, Christian Scimiterna   +10 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Quantum metrology with linear Lie algebra parameterizations

Physical Review Research
Lie algebraic techniques are powerful and widely used tools for studying dynamics and metrology in quantum optics. When the Hamiltonian generates a Lie algebra with finite dimension, the unitary evolution can be expressed as a finite product of ...
Ruvi Lecamwasam, Tatiana Iakovleva, Jason Twamley   +2 more
doaj   +1 more source

Piecewise-Analytical Approximation Methods for Initial-Value Problems of Nonlinear, Ordinary Differential Equations: Part 2

Mathematics
A variety of methods that provide approximate piecewise- analytical solutions to initial-value problems governed by scalar, nonlinear, first-order, ordinary differential equations is presented.
Juan I. Ramos
doaj   +1 more source

Asymptotic Methods for Solitary Solutions and Compactons

Abstract and Applied Analysis, 2012
This paper is an elementary introduction to some new asymptotic methods for the search for the solitary solutions of nonlinear differential equations, nonlinear differential-difference equations, and nonlinear fractional differential equations ...
Ji-Huan He
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Numerical Approximate Solution of Fuzzy Volterra Nonlinear Integro-Differential Equation

Academic Science Journal
In this work, approximate solutions to fuzzy integro-differential equations refer to numerical methods or techniques used to obtain approximate solutions to differential equations involving fuzzy sets and integro-differential operators.
walaa fasial, Rokan Khaji, Suhad K. Hameed   +2 more
doaj   +1 more source

Projection schemes for stochastic partial differential equations

, 2009
The focus of the present work is to develop stochastic reduced basis methods (SRBMs) for solving partial differential equations (PDEs) defined on random domains and nonlinear stochastic PDEs (SPDEs).
Prerapa, Surya Mohan
core